Imaging

Select Publications

• Akaaboune et al. Distinct roles of the dystrophin-glycoprotein complex: α-dystrobrevin and α-syntrophin in the maintenance of the postsynaptic apparatus of the neuromuscular synapse. Hum Mol Genet. 2022.

• Akaaboune M et al. Rapid and reversible effects of activity on acetylcholine receptor density at the neuromuscular junction in vivo. Science. 1999.

• Akaaboune M et al. Neurotransmitter Receptor Dynamics Studied in vivo by Reversible Photo-Unbinding of Fluorescent Ligands. Neuron. 2002.

• Akaaboune M et al. Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin. J Cell Biol. 2011.

• Akaaboune M et al. AChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living Mice. J Neurosci. 2016.

• Akaaboune M et al. The disassembly of the neuromuscular synapse in high-fat diet-induced obese male mice. Mol Metab. 2020.

• Alford AI et al. Two molecular weight species of thrombospondin-2 are present in bone and differentially modulated in fractured and nonfractured tibiae in a murine model of bone healing. Calcif Tissue Int. 2012.

• Alford AI et al. Thrombospondin-2 facilitates assembly of a type-I collagen rich matrix in marrow stromal cells undergoing osteoblastic differentiation. Connect Tissue Res. 2013.

• Alford AI et al. Thrombospondin-2 deficiency in growing mice alters bone collagen ultrastructure and leads to a brittle bone phenotype. J Appl Physiol. 1985.

• Alford AI et al. TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro. Connect Tissue Res. 2019.

• Alford AI et al. Evaluation of global gene expression in regenerate tissues during Masquelet treatment. J Orthop Res. 2020.

• Alford AI et al. Intersite reliability of vertebral bone marrow lipidomics-derived lipid composition among children with varying degrees of bone fragility undergoing routine orthopedic surgery. Bone. 2021.

• Alford AI et al. Pattern of bone marrow lipid composition measures along the vertebral column: A descriptive study of adolescents with idiopathic scoliosis. Bone. 2021.

• Alford AI et al. Masquelet’s induced membrane technique: Review of current concepts and future directions. J Orthop Res. 2021.

• Alford et al. Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone. 2021.

• Allen BL et al. Dosage-dependent regulation of pancreatic cancer growth and angiogenesis by hedgehog signaling. Cell Rep. 2014.

• Allen BL et al. Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function. J Biol Chem. 2015.

• Allen BL et al. Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif. J Biol Chem. 2017.

• Allen BL et al. The Hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development. Development. 2020.

• Allen BL et al. Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer. Clin Cancer Res. 2021.

• Allen et al. Unique lingual expression of the Hedgehog pathway antagonist Hedgehog-interacting protein in filiform papillae during homeostasis and ectopic expression in fungiform papillae during Hedgehog signaling inhibition. Dev Dyn. 2022.

• Allen et al. C-X-C motif chemokine ligand 1 induced by Hedgehog signaling promotes mouse extrahepatic bile duct repair after acute injury. Hepatology. 2022.

• Allen et al. Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer. PLoS Genet. 2022.

• Collins CA et al. Mitochondrial fission, integrity and clearance require separable functions of Vps13D in Drosophila neurons. bioRxiv. 2020.

• Collins CA et al. Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol. 2010.

• Collins CA et al. The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol. 2012.

• Collins CA et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. eLife. 2016.

• Collins CA et al. Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. Elife. 2017.

• Collins CA et al. Regulation of longevity by depolarization-induced activation of PLC-β-IP 3 R signaling in neurons. Proc Natl Acad Sci U S A. 2021.

• Collins CA et al. An NAD+/NMN balancing act by SARM1 and NMNAT2 controls axonal degeneration. J Neuron. 2021.

• Deng CX et al. Injectable pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivo. Sci Rep. 2020.

• Deng CX et al. Microscale Characterization of the Viscoelastic Properties of Hydrogel Biomaterials using Ultrasound Technique. Biomaterials. 2016.

• Deng CX et al. Acoustic tweezing cytometry enhances osteogenesis of human mesenchymal stem cells through cytoskeletal contractility and YAP activation. Biomaterials. 2017.

• Deng CX et al. Multimode Ultrasound Viscoelastography for Three-Dimensional Interrogation of Microscale Mechanical Properties in Heterogeneous Biomaterials. Biomaterials. 2018.

• Deng CX et al. Acoustic actuation of integrin-bound microbubbles for mechanical phenotyping during differentiation and morphogenesis of human embryonic stem cells. Small. 2018.

• Deng CX et al. Integrin-targeted Cyclic Forces Accelerate Neural Tube-like Rosette Formation from Human Embryonic Stem Cells. Adv Biosyst. 2019.

• Deng CX et al. Visualization and quantification of dynamic intercellular coupling in human embryonic stem cells using single cell sonoporation. Sci Rep. 2020.

• Deng CX et al. Resonant acoustic rheometry for non-contact characterization of viscoelastic biomaterials. Biomaterials. 2021.

• Deng CX et al. High Frequency Spectral Ultrasound Imaging Detects Early Heterotopic Ossification in Rodents. Stem Cells Dev. 2021.

• Duan C et al. Hypoxia converts the myogenic action of insulin-like growth factors into mitogenic action by differentially regulating multiple signaling pathways. Proc Natl Acad Sci U S A. 2010.

• Duan C et al. Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Cell Rep. 2014.

• Duan C et al. Ca2+ concentration-dependent premature death of igfbp5a mutant zebrafish reveals a critical role of IGF signaling in adaptive epithelial growth. Sci Signal. 2018.

• Duan C et al. Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6. Elife. 2019.

• Duan C et al. The metalloproteinase Papp-aa controls epithelial cell quiescence to proliferation transition. Elife. 2020.

• Duan et al. Calcium State-Dependent Regulation of Epithelial Cell Quiescence by Stanniocalcin 1a. Front Cell Dev Biol. 2021.

• Duan et al. IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish. Gen Comp Endocrinol. 2021.

• Fabiilli et al. Release of basic fibroblast growth factor from acoustically-responsive scaffolds promotes therapeutic angiogenesis in the hind limb ischemia model. J Control Release. 2021.

• Fabiilli et al. Spatially-directed angiogenesis using ultrasound-controlled release of basic fibroblast growth factor from acoustically-responsive scaffolds. Acta Biomater. 2021.

• Fabiilli et al. Spatiotemporal control of myofibroblast activation in acoustically-responsive scaffolds via ultrasound-induced matrix stiffening. Acta Biomater. 2022.

• Fabiilli et al. Micropatterning of acoustic droplet vaporization in acoustically-responsive scaffolds using extrusion-based bioprinting. Bioprinting. 2022.

• Fabiilli et al. Slow-Flow Ultrasound Localization Microscopy Using Recondensation of Perfluoropentane Nanodroplets. Ultrasound Med Biol. 2022.

• Fabiilli et al. Multi-time scale characterization of acoustic droplet vaporization and payload release of phase-shift emulsions using high-speed microscopy. Ultrason Sonochem. 2022.

• Fabiilli ML et al. Spatiotemporally-controlled transgene expression in hydroxyapatite-fibrin composite scaffolds using high intensity focused ultrasound. Biomaterials. 2019.

• Fabiilli ML et al. Controlled delivery of basic fibroblast growth factor (bFGF) using acoustic droplet vaporization stimulates endothelial network formation. Acta Biomater. 2019.

• Fabiilli ML et al. Standing wave-assisted acoustic droplet vaporization for single and dual payload release in acoustically-responsive scaffolds. Ultrason Sonochem. 2020.

• Fabiilli ML et al. Spatially-directed cell migration in acoustically-responsive scaffolds via the controlled delivery of basic fibroblast growth factor. Acta Biomater. 2020.

• Fabiilli ML et al. Spatiotemporal control of micromechanics and microstructure in acoustically-responsive scaffolds using acoustic droplet vaporization. Soft Matter. 2020.

• Fabiilli ML et al. Stable and transient bubble formation in acoustically-responsive scaffolds by acoustic droplet vaporization: theory and application in sequential release. Ultrason Sonochem. 2021.

• Feldman EL et al. Human neural stem cell transplantation into the corpus callosum of Alzheimer’s mice. Ann Clin Transl Neurol. 2017.

• Feldman EL et al. Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS. Ann Clin Transl Neurol. 2018.

• Feldman EL et al. Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s disease. Sci Rep. 2018.

• Feldman EL et al. Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials. Expert Opin Investig Drugs. 2019.

• Feldman EL et al. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2020.

• Feldman EL et al. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2021.

• Feldman EL et al. Diabetic neuropathy in children and youth: New and emerging risk factors. Pediatr Diabetes. 2021.

• Feldman EL et al. Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Neuron. 2021.

• Feldman EL et al. Altered plasma serine and 1-deoxydihydroceramide profiles are associated with diabetic neuropathy in type 2 diabetes and obesity. J Diabetes Complications. 2021.

• Feldman EL et al. Amyotrophic Lateral Sclerosis Survival Associates With Neutrophils in a Sex-specific Manner. Neurol Neuroimmunol Neuroinflamm. 2021.

• Feldman EL et al. Immune-mediated vincristine-induced neuropathy: Unlocking therapies. J Exp Med. 2021.

• Feldman EL et al. Lessons for clinical trial design in Friedreich’s ataxia. Lancet Neurol. 2021.

• Feldman EL et al. Gene expression profiles of diabetic kidney disease and neuropathy in eNOS knockout mice: Predictors of pathology and RAS blockade effects. Faseb J. 2021.

• Feldman EL et al. Plasma lipid metabolites associate with diabetic polyneuropathy in a cohort with type 2 diabetes. Ann Clin Transl Neurol. 2021.

• Feldman EL et al. NK cells associate with ALS in a sex- and age-dependent manner. JCI Insight 2021.

• Feldman EL et al. Inclusion body myositis: small steps towards future advances. Lanc Rheum. 2021.

• Feldman et al. Untargeted metabolomics yields insight into ALS disease mechanisms. J Neurol Neurosurg Psychiatry. 2020.

• Feldman et al. Covid-19 and diabetes: A collision and collusion of two diseases. Diabetes. 2020.

• Feldman et al. Altered plasma serine and 1-deoxydihydroceramide profiles are associated with diabetic neuropathy in type 2 diabetes and obesity. J Diabetes Complications. 2021.

• Feldman et al. Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact. Neurosci Biobehav Rev. 2021.

• Feldman et al. Association of Variants in the SPTLC1 Gene with Juvenile Amyotrophic Lateral Sclerosis. JAMA Neurol. 2021.

• Feldman et al. Dietary weight loss in people with severe obesity stabilizes neuropathy and improves symptomatology. Obesity (Silver Spring). 2021.

• Feldman et al. Advances in diet-induced rodent models of metabolically acquired peripheral neuropathy. Dis Model Mech. 2021.

• Feldman et al. Nox, Nox, Are You There? the Role of NADPH Oxidases in the Peripheral Nervous System. Antioxid Redox Signal. 2022.

• Feldman et al. Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts. Brain. 2022.

• Feldman et al. A Role for Fatty Acids in Peripheral Neuropathy Associated with Type 2 Diabetes and Prediabetes. Antioxid Redox Signal. 2022.

• Feldman et al. Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis. Front Immunol. 2022.

• Feldman et al. Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis. Lancet Neurol. 2022.

• Feldman et al. Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis. Lancet Neurol. 2022.

• Feldman et al. Neurological sequela and disruption of neuron-glia homeostasis in SARS-CoV-2 infection. Neurobiol Dis. 2022.

• Feldman et al. Glial-neuron crosstalk in health and disease: A focus on metabolism, obesity, and cognitive impairment. Neurobiok Dis. 2022.

• Feldman et al. Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes. Ann Clin Transl Neurol. 2022.

• Feldman et al. Amyotrophic lateral sclerosis from genotoxins alone? – Authors’ reply. Lancet Neurol. 2022.

• Feldman et al. Towards prevention of diabetic peripheral neuropathy: clinical presentation, pathogenesis, and new treatments. Lancet Neurol. 2022.

• Feldman et al. Diabetes and dementia: Clinical perspective, innovation, knowledge gaps. J Diabetes Complications. 2022.

• Feldman et al. The conundrum of diabetic neuropathies—Past, present, and future. J Diabetes Complications. 2022.

• Feldman et al. ISPAD Clinical Practice Consensus Guidelines 2022: Microvascular and macrovascular complications in children and adolescents with diabetes. Pediatr Diabetes. 2022.

• Feldman et al. Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice. Immun Ageing. 2022.

• Feldman et al.Differential effects of empagliflozin on microvascular complications in murine models of type 1 and type 2 diabetes. Biology (Basel). 2020

• Goldman D et al. A role for alpha1 tubulin-expressing Müller glia in regeneration of the injured zebrafish retina. J Neurosci. 2006.

• Goldman D et al. Ascl1a regulates Müller glia dedifferentiation and retina regeneration via a Lin-28-dependent, let-7 miRNA signaling pathway. Nat Cell Biol. 2010.

• Goldman D et al. HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration. Dev Cell. 2012.

• Goldman D et al. Analysis of DNA methylation reveals a partial reprogramming of the Müller glia genome during retina regeneration. Proc Natl Acad Sci U S A. 2013.

• Goldman D et al. Tgfb3 collaborates with PP2A and Notch signaling pathways to inhibit retina regeneration. Elife. 2020.

• Goldman et al. Notch signaling via Hey1 and Id2b regulates Müller glia’s regenerative response to retinal injury. Glia. 2021.

• Goldman et al. Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration. Proc Natl Acad Sci U S A. 2022.

• Hammoud et al. Regulation of meiotic progression by Sertoli-cell androgen signaling. Mol Biol Cell. 2020.

• Heemskerk et al. Stable iPSC-derived NKX2-1+ lung bud tip progenitor organoids give rise to airway and alveolar cell types. Development. 2022.

• Heemskerk I Full of potential: Pluripotent stem cells for the systems biology of embryonic patterning. Dev Biol. 2020.

• Heemskerk I et al. Tissue cartography: compressing bio-image data by dimensional reduction. Nat Methods. 2015.

• Heemskerk I et al. Differential growth triggers mechanical feedback that elevates Hippo signaling. Proc Natl Acad Sci U S A. 2016.

• Heemskerk I et al. Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells. Elife. 2019.

• Heemskerk I et al. Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Phys Biol. 2021.

• Hitchcock PF et al. The bHLH Transcription Factor NeuroD Governs Photoreceptor Genesis and Regeneration Through Delta-Notch Signaling. Invest Ophthalmol Vis Sci. 2015.

• Hitchcock PF et al. The MicroRNA, miR-18a, Regulates NeuroD and Photoreceptor Differentiation in the Retina of Zebrafish. Dev Neurobiol. 2019.

• Hitchcock PF et al. Midkine-a Is Required for Cell Cycle Progression of Müller Glia during Neuronal Regeneration in the Vertebrate Retina. J Neurosci. 2020.

• Hitchcock PF et al. Inflammation and matrix metalloproteinase 9 (Mmp-9) regulate photoreceptor regeneration in adult zebrafish. Glia. 2020.

• Hitchcock PF et al. Reprogramming Mller Glia to Regenerate Retinal Neurons. Annu Rev Vis Sci. 2020.

• Isom et al.Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP. Mol Psychiatry. 2020

• Isom et al.Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52. Ann Clin Transl Neurol. 2020

• Isom LL et al. SCN1B-linked early infantile developmental and epileptic encephalopathy. Ann Clin Transl Neurol. 2019.

• Isom LL et al. Voltage-gated sodium channel ß1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis. J Biol Chem. 2020.

• Isom LL et al. Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome. Sci Transl Med. 2020.

• Isom LL et al. Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons. Brain. 2020.

• Isom LL et al. Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52. Ann Clin Transl Neurol. 2020.

• Kohn DH et al. Connexin 43 as a signaling platform for increasing the volume and spatial distribution of regenerated tissue. Proc Natl Acad Sci U S A. 2009.

• Kohn DH et al. Gene delivery via DNA incorporation within a biomimetic apatite coating. Biomaterials. 2009.

• Kohn DH et al. PTH signaling mediates perilacunar remodeling during exercise. Matrix Biol. 2016.

• Kohn DH et al. Dual-functioning peptides discovered by phage display increase the magnitude and specificity of BMSC attachment to mineralized biomaterials. Biomaterials. 2017.

• Kohn DH et al. Cell and material-specific phage display peptides increase iPS-MSC mediated bone and vasculature formation in vivo. Adv Healthc Mater. 2019.

• Kohn DH et al. Translating Dental, Oral, and Craniofacial Regenerative Medicine Innovations to the Clinic through Interdisciplinary Commercial Translation Architecture. J Dent Res. 2021.

• Kohn et al. Region-specific associations among tissue-level mechanical properties, porosity, and composition in human male femora. J Biomech. 2022.

• Kohn et al. Divergent mechanical properties of older human male femora reveal unique combinations of morphological and compositional traits contributing to low strength. Bone. 2022.

• Kohn et al. Sex and External Size Specific Limitations in Assessing Bone Health From Adult Hand Radiographs. JBMR Plus. 2022.

• Kozloff et al. Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone. 2021.

• Kozloff et al. Systemic administration of recombinant irisin accelerates fracture healing in mice. Int J Mol Sci. 2021.

• Kozloff et al. Position-Specific Physical Workload Intensities in American Collegiate Football Training. J Strength Cond Res. 2022.

• Kozloff et al. Tibial nerve stimulation increases vaginal blood perfusion and bone mineral density and yield load in ovariectomized rat menopause model. Int Urogynecol J. 2022.

• Kozloff et al. Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study. J Struct Biol. 2022.

• Kozloff et al.Bone chemical composition assessment with multi-wavelength photoacoustic analysis. Front Physics. 2020

• Kozloff KM et al. Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo. J Bone Miner Res. 2010.

• Kozloff KM et al. Osteoblast response to ovariectomy is enhanced in intrinsically high aerobic capacity rats. Calcif Tissue Int. 2011.

• Kozloff KM et al. Adult Brtl/+ mouse model of osteogenesis imperfecta demonstrates anabolic response to sclerostin antibody treatment with increased bone mass and strength. Osteoporos Int. 2014.

• Kozloff KM et al. Rapidly growing Brtl/+ mouse model of osteogenesis imperfecta improves bone mass and strength with sclerostin antibody treatment. Bone. 2015.

• Kozloff KM et al. Low dose of bisphosphonate enhances sclerostin antibody-induced trabecular bone mass gains in Brtl/+ osteogenesis imperfecta mouse model. J Bone Miner Res. 2018.

• Kozloff KM et al. In vivo quantitative imaging biomarkers of bone quality and mineral density using multi-band-SWIFT magnetic resonance imaging. Bone. 2021.

• Kozloff KM et al. Altered collagen chemical compositional structure in osteopenic women with past fractures: A case-control Raman spectroscopic study. Bone. 2021.

• Kozloff KM et al. The feasibility study of the transmission mode photoacoustic measurement of human calcaneus bone in vivo. Photoacoustics. 2021.

• Kozloff, KM et al. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020.

• Kruger et al. Acupressure for cancer-fatigue in ovarian cancer survivor (The AcuOva Study): A community-based clinical trial study protocol examining the impact of self-acupressure on persistent cancer related fatigue in ovarian cancer survivors. Contemp Clin Trials. 2021.

• Kruger et al. Experimental Pain and Auditory Sensitivity in Overactive Bladder Syndrome: A Symptoms of the Lower Urinary Tract Dysfunction Research Network (LURN) Study. J Urol. 2022.

• Kruger et al. Reply by Authors. J Urol. 2022.

• Mishina et al. Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions. Genesis. 2021.

• Mishina et al. Chondrocyte Tsc1 controls cranial base bone development by restraining the premature differentiation of synchondroses. Bone. 2021.

• Mishina et al. Podoplanin is dispensable for mineralized tissue formation and maintenance in the Swiss outbred mouse background. Genesis. 2021.

• Mishina et al. Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development. Transgenic Res. 2022.

• Mishina et al. Roles of osteoclasts in alveolar bone remodeling. Genesis. 2022.

• Mishina et al. Activation of AcvR1-Mediated Signaling Results in Semilunar Valve Defects. J Cardiovasc Dev Dis. 2022.

• Mishina et al. Enhanced BMP signaling through ALK2 attenuates keratinocyte differentiation. Biochem Biophys Res Commun. 2022.

• Mishina Y et al. Quantification of three-dimensional morphology of craniofacial mineralized tissue defects in Tgfbr2/Osx-Cre mice. Oral Sci Int. 2021.

• Mishina Y et al. Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation. Sci Signal. 2021.

• Mishina Y et al. Quantification of three-dimensional morphology of craniofacial mineralized tissue defects in Tgfbr2/Osx-Cre mice. Oral Sci Int. 2021.

• Mishina Y et al. BMP type I receptor inhibition prevents ectopic ossification in a mouse model of fibrodysplasia ossificans progressiva. Nat Med. 2008.

• Mishina Y et al. Augmented BMP signaling in neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis. Development. 2015.

• Mishina Y et al. Coordinating Tissue Regeneration Through Transforming Growth Factor-β Activated Kinase 1 Inactivation and Reactivation. Stem Cells. 2019.

• Mishina Y et al. Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway. J Biol Chem. 2019.

• Mishina Y et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020.

• Mishina Y et al. Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes depending on anatomical positions of the bones in mice. Bone. 2020.

• Mishina Y et al. Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis. J Cell Physiol. 2021.

• Mishina Y et al. ALK3 Is Not Required for the Embryonic Development, Homeostasis, and Repopulation of Epidermal Langerhans Cells in Steady and Inflammatory States. J Invest Dermatol. 2021.

• Mishina Y et al. Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution. Nat Genet. 2021.

• Mishina Y et al. Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate. Biomaterials. 2021.

• Mishina Y et al. mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways. Cell Rep. 2021.

• Mistretta et al. The fungiform papilla is a complex, multimodal, oral sensory organ. Curr Opin Physiol. 2021.

• Mistretta et al. Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition. Cell Tissue Res. 2022.

• Mistretta et al. Unique lingual expression of the Hedgehog pathway antagonist Hedgehog-interacting protein in filiform papillae during homeostasis and ectopic expression in fungiform papillae during Hedgehog signaling inhibition. Dev Dyn. 2022.

• Mistretta et al. Correction to: Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition (Cell and Tissue Research, (2022), 387, 2, (225-247), 10.1007/s00441-021-03561-1). Cell Tissue Res. 2022.

• Mistretta et al. High-sucrose diet exposure is associated with selective and reversible alterations in the rat peripheral taste system. Curr Biol. 2022.

• Moon JJ et al. Modularly Programmable Nanoparticle Vaccine Based on Polyethyleneimine for Personalized Cancer Immunotherapy. Adv Sci. 2021.

• Moon JJ et al. Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport. J Control Rel. 2021.

• Mycek et al. Reconstruction of optical coefficients in turbid media using time-resolved reflectance and calibration-free instrument response functions. Biomed Opt Express. 2022.

• Mycek et al. Noninvasive Optical Assessment of Implanted Tissue-Engineered Construct Success in Situ. Tissue Eng Part C Methods. 2021.

• Mycek et al.Needle-compatible miniaturized optoelectronic sensor for pancreatic cancer detection. Sci Adv. 2020

• Ono N et al. Diverse contribution of Col2a1-expressing cells to the craniofacial skeletal cell lineages. Orthod Craniofac Res. 2017.

• Ono N et al. Msx2 Marks Spatially Restricted Populations of Mesenchymal Precursors. J Dent Res. 2018.

• Ono N et al. Resting zone of the growth plate houses a unique class of skeletal stem cells. Nature. 2018.

• Ono N et al. Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells. J Bone Miner Res. 2019.

• Ono N et al. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020.

• Ono N et al. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020.

• Parkos CA et al. JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med. 2007.

• Parkos CA et al. Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis. Immunity. 2012.

• Parkos CA et al. Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation. Mucosal Immunol. 2014.

• Parkos CA et al. Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo. Nat Commun. 2019.

• Parkos CA et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020.

• Parkos CA et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2021.

• Parkos CA et al. Dysregulation of intestinal epithelial CFTR-dependent Cl− ion transport and paracellular barrier function drives gastrointestinal symptoms of food-induced anaphylaxis in mice. Mucosal Ummunol. 2021.

• Parkos CA et al. Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2. Mol Biol Cell. 2021.

• Parkos et al. Sialylation of CD11b/CD18 regulates Neutrophil Transepithelial Migration and Neutrophil Inflammatory function in the Intestine. FASEB J. 2022.

• Parkos et al. Finding the sweet spot: glycosylation mediated regulation of intestinal inflammation. Mucosal Immunol. 2022.

• Parkos et al. SIRPα – CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen. PLoS One. 2022.

• Parkos et al. JAM-A signals through the Hippo pathway to regulate intestinal epithelial proliferation. iScience. 2022.

• Parkos et al. Junctional adhesion molecule-A deletion increases phagocytosis and improves survival in a murine model of sepsis. JCI Insight. 2022.

• Parkos et al. Epithelial JAM-A is fundamental for intestinal wound repair in vivo. JCI Insight. 2022.

• Parkos et al. Intestinal epithelial BLT1 promotes mucosal repair. JCI Insight. 2022.

• Rajapakse et al. Understanding memory B cell selection. J Theor Biol. 2021.

• Rajapakse et al. Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters. JCI Insight. 2022.

• Rajapakse et al. Functional organization of the maternal and paternal human 4D Nucleome. iScience. 2021.

• Rajapakse I et al. On Emerging Nuclear order. J Cell Biol. 2011.

• Rajapakse I et al. Dynamics and control of state-dependent networks for probing genomic organization. Proc Natl Acad Sci U S A. 2011.

• Rajapakse I et al. Functional organization of the human 4D Nucleome. Proc Natl Acad Sci U S A. 2015.

• Rajapakse I et al. Emergence of function from coordinated cells in a tissue. Proc Natl Acad Sci U S A. 2017.

• Rajapakse I et al. An Algorithm for Cellular Reprogramming. Proc Natl Acad Sci U S A. 2017.

• Rajapakse I et al. TCF7L2 silencing results in altered gene expression patterns accompanied by local genomic reorganization. Neoplasia. 2021.

• Rajapakse I et al. Network dynamics of hypothalamic feeding neurons. Proc Natl Acad Sci U S A. 2021.

• Ross et al. Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution. Nat Commun. 2020.

• Ross et al. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem 2022.

• Ross et al. Technical note: Temperature and concentration dependence of water diffusion in polyvinylpyrrolidone solutions. Med Phys. 2022.

• Ross et al. Multiparametric MRI to quantify disease and treatment response in mice with myeloproliferative neoplasms. JCI Insight. 2022.

• Saitou et al. A novel predictive-reactive rescheduling method for products assembly lines with optimal dynamic pegging. Comput Ind Eng. 2022.

• Saitou K et al. Anisotropic multicomponent topology optimization for additive manufacturing with build orientation design and stress-constrained interfaces. ASME 2019. 2019.

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