Nerve Repair/​Neuroengineering

Select Publications

• Aguilar CA et al. Transcriptional and Chromatin Dynamics of Muscle Regeneration After Severe Trauma. Stem Cell Reports. 2016.

• Aguilar CA et al. Multiscale analysis of a regenerative therapy for treatment of volumetric muscle loss injury. Cell Death Discov. 2018.

• Aguilar CA et al. Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis. J Immunology. 2020.

• Aguilar CA et al. Dissecting murine muscle stem cell aging through integrative genomic analysis. Cell Rep. 2020.

• Aguilar CA et al. Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells. JCI Insight. 2020.

• Aguilar CA et al. Engineered Tools to Study Intercellular Communication. Adv Sci (Weinh). 2021.

• Aguilar CA et al. Metabolipidomic profiling reveals an age-related deficiency of skeletal muscle pro-resolving mediators that contributes to maladaptive tissue remodeling. Aging Cell. 2021.

• Aguilar CA et al. Sestrins regulate muscle stem cell metabolic homeostasis. Stem Cell Reports. 2021.

• Aguilar et al. Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss. Commun Biol. 2020.

• Aguilar et al. Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss. Proc Natl Acad Sci U S A. 2022.

• Akaaboune M et al. Rapid and reversible effects of activity on acetylcholine receptor density at the neuromuscular junction in vivo. Science. 1999.

• Akaaboune M et al. Neurotransmitter Receptor Dynamics Studied in vivo by Reversible Photo-Unbinding of Fluorescent Ligands. Neuron. 2002.

• Akaaboune M et al. Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin. J Cell Biol. 2011.

• Akaaboune M et al. AChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living Mice. J Neurosci. 2016.

• Akaaboune M et al. The disassembly of the neuromuscular synapse in high-fat diet-induced obese male mice. Mol Metab. 2020.

• Alford AI et al. Intersite reliability of vertebral bone marrow lipidomics-derived lipid composition among children with varying degrees of bone fragility undergoing routine orthopedic surgery. Bone. 2021.

• Alford AI et al. Masquelet’s induced membrane technique: Review of current concepts and future directions. J Orthop Res. 2021.

• Alford et al. Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone. 2021.

• Arruda et al. Investigation of Fiber-Driven Mechanical Behavior of Human and Porcine Bladder Tissue Tested Under Identical Conditions. J Biomech Eng. 2021.

• Arruda et al. Constitutive modeling of the anterior cruciate ligament bundles and patellar tendon with full-field methods. J Mech Phys Solids. 2021.

• Arruda et al. Inference of deformation mechanisms and constitutive response of soft material surrogates of biological tissue by full-field characterization and data-driven variational system identification. J Mech A Solid 2021.

• Besirli et al. Association of metformin and development of dry age-related macular degeneration in a U.S. insurance claims database. Eur J Ophthalmol. 2022.

• Besirli et al. Perifoveal Chorioretinal Atrophy after Subretinal Voretigene Neparvovec-rzyl for RPE65-Mediated Leber Congenital Amaurosis. Ophthalmol Retina. 2022.

• Besirli et al. Referable Macular Hemorrhage-A Clinically Meaningful Screening Target in Newborn Infants. Position Statement of the Association of Pediatric Retina Surgeons. Ophthalmic Surg Lasers Imaging Retina. 2022.

• Besirli et al. Surgical repair of primary non-complex rhegmatogenous retinal detachment in the modern era of small-gauge vitrectomy. BMJ Open Opthalmology 2021.

• Besirli et al. Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, circumvents photoreceptor apoptosis. Sci Rep. 2020.

• Besirli et al. Coats-like Exudative Vitreoretinopathy in Retinitis Pigmentosa: Ocular Manifestations and Treatment Outcomes. Opthalmol Retina. 2021.

• Besirli et al. Cryotherapy for the management of refractory hypotony secondary to post-goniotomy cyclodialysis cleft. Am J Ophthalmol Case Rep. 2020.

• Besirli et al. Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort. Sci Rep. 2020.

• Besirli et al. A novel OCT signature in leukemic papillopathy masquerading as autoimmune or infectious uveitis. Graefes Arch Clin Exp Opthalmol. 2021.

• Besirli et al. Autophagy activation and photoreceptor survival in retinal detachment. Exp Eye Res. 2021.

• Besirli et al. Scleral Histopathologic Findings of Hurler-Scheie Syndrome with Refractory Glaucoma. JAMA Ophthalmol. 2022.

• Besirli, et al. Characteristics of Retinal Detachment after Pediatric Open-Globe Injuries. Ophthalmol Retina. 2021.

• Buchman et al. Association between habitual snoring, middle ear disease, and speech problems in young children with non-syndromic cleft palate anomalies. Int J Oral Maxillofac Surg. 2022.

• Buchman et al. Impact of sleep-disordered breathing on behavior and quality of life in children aged 2 to 7 years with non-syndromic cleft lip and/or palate. Pediatr Pulmonol. 2021.

• Buchman SR et al. Radioprotection With Amifostine Enhances Bone Strength and Regeneration and Bony Union in a Rat Model of Mandibular Distraction Osteogenesis. Ann Plast Surg. 2018.

• Buchman SR et al. Topical Deferoxamine Alleviates Skin Injury and Normalizes Atomic Force Microscopy Patterns Following Radiation in a Murine Breast Reconstruction Model. Ann Plast Surg. 2018.

• Buchman SR et al. Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment. J Craniofac Surg. 2019.

• Buchman SR et al. The Role of Deferoxamine in Irradiated Breast Reconstruction: A Study of Oncologic Safety. Plast Reconstr Sur. 2019.

• Buchman SR et al. Implantable hyaluronic acid-deferoxamine conjugate prevents nonunions through stimulation of neovascularization. NPJ Regen Med. 2019.

• Buchman SR et al. A Simplified Approach to Myelomeningocele Defect Repair. Ann Plast Surg. 2021.

• Buchman SR et al. Achieving the Optimal Aesthetic Benefit While Correcting Midface Deficiency: Utilizing A High Winged Le Fort I in Cleft and Craniofacial Patients. J Craniofac Surg. 2021.

• Buchman SR et al. Sleep-related movement disorders and growing pains: differences in daytime and bedtime behavior in 2–6 year old children with cleft palate. Sleep Med. 2021.

• Cederna et al. Commentary on: Resident Exposure to Aesthetic Surgical and Nonsurgical Procedures during Canadian Residency Program Training. Aesthet Surg J. 2021.

• Cederna et al. Comparison of Outcomes of Spinal Accessory to Suprascapular Nerve Transfer Versus Nerve Grafting for Neonatal Brachial Plexus Injury. Orthopedics. 2022.

• Cederna et al. The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals. J Vis Exp. 2022.

• Cederna et al. Aesthetic Surgery in Plastic Surgery Academia. Aesthet Surg J. 2021.

• Cederna et al. Regenerative Peripheral Nerve Interfaces for Advanced Control of Upper Extremity Prosthetic Devices. Hand Clin. 2021.

• Cederna et al. Neuroma, Neural Interface, and Prosthetics. Hand Clin. 2021.

• Cederna et al. “Decreasing Postamputation Pain with the Regenerative Peripheral Nerve Interface (RPNI)”. Ann Vasc Surg. 2022.

• Cederna PS et al. Chronic Recording of Hand Prosthesis Control Signals Via a Regenerative Peripheral In a Rhesus Macaque. J Neural Eng. 2016.

• Cederna PS et al. The Regenerative Peripheral Nerve Interface for Neuroma Management. JAMA Surg. 2018.

• Cederna PS et al. Prosthetic Rehabilitation and Vascularized Composite Allotransplantation Following Upper Limb Loss. Plast Reconstr Surg. 2019.

• Cederna PS et al. Prophylactic Regenerative Peripheral Nerve Interfaces (RPNIs) to Prevent Postamputation Pain. Plast Reconstr Surg. 2019.

• Cederna PS et al. A Regenerative Peripheral Nerve Interface Allows Real-Time Control of an Artificial Hand In Upper Limb Amputees. Sci Transl Med. 2020.

• Cederna PS et al. Reinventing Extremity Amputation in the Era of Functional Limb Restoration. Ann Surg. 2021.

• Cederna PS et al. Developing Strategies for Targeted Improvement of Perioperative Education for Postbariatric Surgery Body-Contouring Patients. Ann Plast Surg. 2021.

• Cederna PS et al. Commentary on: Trends and challenges of telehealth in an academic institution: The unforeseen benefits of the COVID-19 global pandemic. Aesthet Surg J. 2021.

• Cederna PS et al. Impact of Human Epidermal Growth Factor on Tissue-Engineered Skeletal Muscle Structure and Function. Tissue Eng Part A. 2021.

• Cederna PS et al. Regenerative peripheral nerve interface free muscle graft mass and function. Muscle Nerve. 2021.

• Cederna PS et al.The clinical significance of a swollen neuroma: A meaningful distinction or an incidental finding? Ann Palliat Med. 2020

• Chen et al. Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy. Cardiovasc Drugs Ther. 2021.

• Chen et al. Genetically Modified Rabbits for Cardiovascular Research. Front Genet. 2021.

• Chen et al. Risk factors for heart transplant survival with greater than 5 h of donor heart ischemic time. J Card Surg. 2021.

• Chen et al. Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway. J Mol Cell Cardiol. 2022.

• Chen et al. RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II. Pharmacol Res. 2022.

• Chen YE et al. Roles of Perivascular Adipose Tissue in Hypertension and Atherosclerosis. Antioxid Redox Signal. 2021.

• Chen YE et al. KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction. JCI Insight. 2021.

• Chen YE et al. Translating Cardiovascular Genomics to Clinical Practice. Cardiovasc Drugs Ther. 2021.

• Chen YE et al. Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases. Cardiovasc Drugs Ther. 2021.

• Chen YE et al. Improving the genome assembly of rabbits with long-read sequencing. Genomics. 2021.

• Chen YE et al. Biomimetic tubular scaffold with heparin conjugation for rapid degradation in in situ regeneration of a small diameter neoartery. Biomaterials. 2021.

• Chen YE et al. Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm. Am J Hum Genet. 2021.

• Coleman et al. Engineering Closed-Loop, Autoregulatory Gene Circuits for Osteoarthritis Cell-Based Therapies. Curr Rheumatol Rep. 2022.

• Collins CA et al. Mitochondrial fission, integrity and clearance require separable functions of Vps13D in Drosophila neurons. bioRxiv. 2020.

• Collins CA et al. Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol. 2010.

• Collins CA et al. The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol. 2012.

• Collins CA et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. eLife. 2016.

• Collins CA et al. Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. Elife. 2017.

• Duncan RK et al. The intrinsic electrophysiological properties of neurons derived from mouse embryonic stem cells overexpressing neurogenin-1. Am J Physiol Cell Physiol. 2010.

• Duncan RK et al. Combining topographical and genetic cues to promote neuronal fate specification in stem cells. Biomacromolecules. 2012.

• Duncan RK et al. Survival of human embryonic stem cells implanted in the guinea pig auditory epithelium. Sci Rep. 2017.

• Duncan RK et al. Nanofibrous scaffolds for the guidance of stem cell-derived neurons for auditory nerve regeneration. PLoS One. 2017.

• Duncan RK et al. From Otic Induction to Hair Cell Production: Pax2-EGFP Cell Line Illuminates Key Stages of Development in Mouse Inner Ear Organoid Model. Stem Cell Dev. 2018.

• Feldman EL et al. Human neural stem cell transplantation into the corpus callosum of Alzheimer’s mice. Ann Clin Transl Neurol. 2017.

• Feldman EL et al. Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS. Ann Clin Transl Neurol. 2018.

• Feldman EL et al. Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s disease. Sci Rep. 2018.

• Feldman EL et al. Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials. Expert Opin Investig Drugs. 2019.

• Feldman EL et al. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2020.

• Feldman EL et al. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2021.

• Feldman EL et al. Altered plasma serine and 1-deoxydihydroceramide profiles are associated with diabetic neuropathy in type 2 diabetes and obesity. J Diabetes Complications. 2021.

• Feldman EL et al. Inclusion body myositis: small steps towards future advances. Lanc Rheum. 2021.

• Feldman et al. Untargeted metabolomics yields insight into ALS disease mechanisms. J Neurol Neurosurg Psychiatry. 2020.

• Feldman et al. Covid-19 and diabetes: A collision and collusion of two diseases. Diabetes. 2020.

• Feldman et al.Differential effects of empagliflozin on microvascular complications in murine models of type 1 and type 2 diabetes. Biology (Basel). 2020

• Fu J et al. Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche. Nat Mater. 2017.

• Fu J et al. A pluripotent stem cell-based model for post-implantation human amniotic sac development. Nat Commun. 2017.

• Fu J et al. Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells. Nat Mater. 2018.

• Fu J et al. Controlled modeling of human epiblast and amnion development using stem cells. Nature. 2019.

• Fu J et al. Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a biomimetic neurogenic niche. Sci Adv. 2019.

• Fu J et al. Visualization and quantification of dynamic intercellular coupling in human embryonic stem cells using single cell sonoporation. Sci Rep. 2020.

• Fu J et al. A microfluidics-based stem cell model of early post-implantation human development. Nat Protoc. 2021.

• Giger RJ et al. Neuroinflammation triggered by ß-glucan/dectin-1 signaling enables CNS axon regeneration. Proc Natl Acad Sci U S A. 2015.

• Giger RJ et al. A new neutrophil subset promotes CNS neuron survival and axon regeneration. Nat Immunol. 2020.

• Giger RJ et al. Analysis of the immune response to sciatic nerve injury identified efferocytosis as a key mechanism of nerve debridement. bioRxiv. 2020.

• Goldman D et al. A role for alpha1 tubulin-expressing Müller glia in regeneration of the injured zebrafish retina. J Neurosci. 2006.

• Goldman D et al. Ascl1a regulates Müller glia dedifferentiation and retina regeneration via a Lin-28-dependent, let-7 miRNA signaling pathway. Nat Cell Biol. 2010.

• Goldman D et al. HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration. Dev Cell. 2012.

• Goldman D et al. Analysis of DNA methylation reveals a partial reprogramming of the Müller glia genome during retina regeneration. Proc Natl Acad Sci U S A. 2013.

• Goldman D et al. Tgfb3 collaborates with PP2A and Notch signaling pathways to inhibit retina regeneration. Elife. 2020.

• Green GE et al. A 3D-printed Lateral Skull Base Implant for Repair of Tegmen Defects. Otol Neurotol. 2020.

• Isom et al. Gastrointestinal Symptoms and Channelopathy-Associated Epilepsy. J Pediatr. 2021.

• Isom et al.Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP. Mol Psychiatry. 2020

• Isom et al.Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52. Ann Clin Transl Neurol. 2020

• Isom LL et al. SCN1B-linked early infantile developmental and epileptic encephalopathy. Ann Clin Transl Neurol. 2019.

• Isom LL et al. Voltage-gated sodium channel ß1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis. J Biol Chem. 2020.

• Isom LL et al. Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome. Sci Transl Med. 2020.

• Isom LL et al. Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons. Brain. 2020.

• Isom LL et al. Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52. Ann Clin Transl Neurol. 2020.

• Iwase et al. Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation. Commun Biol. 2020.

• Iwase et al. Soma-to-germline transformation in chromatin-linked neurodevelopmental disorders?. FEBS J. 2022.

• Iwase et al.X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity. J Clin Inveset. 2020

• Iwase S et al. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylase. Cell. 2007.

• Iwase S et al. ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol. 2011.

• Iwase S et al. Sequencing of first-strand cDNA library reveals full-length transcriptomes. Nat Commun. 2015.

• Iwase S et al. RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling. Cell Rep. 2020.

• Kemp et al. Comparison of Outcomes of Spinal Accessory to Suprascapular Nerve Transfer Versus Nerve Grafting for Neonatal Brachial Plexus Injury. Orthopedics. 2022.

• Kemp et al. The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals. J Vis Exp. 2022.

• Kemp et al. Regenerative peripheral nerve interface free muscle graft mass and function. Muscle Nerve. 2021.

• Kemp et al. “Decreasing Postamputation Pain with the Regenerative Peripheral Nerve Interface (RPNI)”. Ann Vasc Surg. 2022.

• Kemp SWP et al.The clinical significance of a swollen neuroma: A meaningful distinction or an incidental finding? Ann Palliat Med. 2020

• Kim et al. Observation of magneto-electric rectification at non-relativistic intensities. Nat Commun. 2020.

• Kozloff et al. Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone. 2021.

• Kozloff et al. Systemic administration of recombinant irisin accelerates fracture healing in mice. Int J Mol Sci. 2021.

• Kozloff et al. Position-Specific Physical Workload Intensities in American Collegiate Football Training. J Strength Cond Res. 2022.

• Kozloff KM et al. In vivo quantitative imaging biomarkers of bone quality and mineral density using multi-band-SWIFT magnetic resonance imaging. Bone. 2021.

• Kozloff KM et al. Altered collagen chemical compositional structure in osteopenic women with past fractures: A case-control Raman spectroscopic study. Bone. 2021.

• Kozloff KM et al. The feasibility study of the transmission mode photoacoustic measurement of human calcaneus bone in vivo. Photoacoustics. 2021.

• Kushner et al. Positive charging of grains in an afterglow plasma is enhanced by ions drifting in an electric field. Phys Plasmas. 2021.

• Kushner et al. Scaling of atomic layer etching of SiO2in fluorocarbon plasmas: Transient etching and surface roughness. J. Vac. Sci. Technol. 2021.

• Kushner et al. Interactions between atmospheric pressure plasmas and metallic catalyst particles in packed bed reactors. J. Phys. D: Appl. Phys. 2021.

• Kushner et al. Electric field reversals resulting from voltage waveform tailoring in Ar/O2capacitively coupled plasmas sustained in asymmetric systems. Plasma Sources Sci. Technol. 2021.

• Kushner et al. Propagation of atmospheric pressure plasmas through interconnected pores in dielectric materials. J Appl Phys. 2021.

• Lahann et al. Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy. Nat Commun. 2020.

• Lahann et al. Overcoming biological barriers to improve solid tumor immunotherapy. Drug Deliv Transl Res.

• Lahann et al. Facile Fabrication of Anisotropic Multicompartmental Microfibers Using Charge Reversal Electrohydrodynamic Co-Jetting. Macromol Rapid Commun. 2022.

• Lahann et al. Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation. Nat Nanotechnol. 2022.

• Lahann et al. Surfaces Decorated with Enantiomorphically Pure Polymer Nanohelices via Hierarchical Chirality Transfer across Multiple Length Scales. Adv Mater. 2022.

• Lahann et al. Coaxial electrospray of uniform polylactide core-shell microparticles for long-acting contraceptive. J Control Release. 2022.

• Lahann et al. Protein Nanoparticles: Uniting the Power of Proteins with Engineering Design Approaches. Adv Sci (Weinh). 2022.

• Lahann J et al. Cooperative Switching in Large‐Area Assemblies of Magnetic Janus Particles. Adv Funct Mater. 2020.

• Lahann J et al. 3D Jet Writing: Functional Microtissues Based on Tessellated Scaffold Architectures. Adv Mater. 2018.

• Lahann J et al. Templated nanofiber synthesis via chemical vapor polymerization into liquid crystalline films. Science. 2018.

• Lahann J et al. Engineered Fibrillar Fibronectin Networks as Three Dimensional Tissue Scaffolds. Adv Mater. 2019.

• Lahann J et al. Multifunctional Synthetic Protein Nanoparticles via Reactive Electrojetting. Macromol Rapid Commun. 2020.

• Lahann J et al. Stepwise cell seeding on tessellated scaffolds to study sprouting blood vessels. J Vis Exp. 2021.

• Lahann J et al. Performance Fabrics Obtained by In Situ Growth of Metal-Organic Frameworks in Electrospun Fibers. ACS Appl Mater Interfaces. 2021.

• Lahann J et al. Targeting gliomas with STAT3-silencing nanoparticles. Mol Cell Onc. 2021.

• Larkin et al. Impact of Human Epidermal Growth Factor on Tissue-Engineered Skeletal Muscle Structure and Function. Tissue Eng Part A. 2021.

• Lempka et al. Quantitative Sensory Testing of Spinal Cord and Dorsal Root Ganglion Stimulation in Chronic Pain Patients. Neuromodulation. 2021.

• Mishina et al. Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions. Genesis. 2021.

• Mishina et al. Chondrocyte Tsc1 controls cranial base bone development by restraining the premature differentiation of synchondroses. Bone. 2021.

• Mishina et al. Podoplanin is dispensable for mineralized tissue formation and maintenance in the Swiss outbred mouse background. Genesis. 2021.

• Mishina Y et al. Quantification of three-dimensional morphology of craniofacial mineralized tissue defects in Tgfbr2/Osx-Cre mice. Oral Sci Int. 2021.

• Mishina Y et al. Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis. J Cell Physiol. 2021.

• Mishina Y et al. ALK3 Is Not Required for the Embryonic Development, Homeostasis, and Repopulation of Epidermal Langerhans Cells in Steady and Inflammatory States. J Invest Dermatol. 2021.

• Mishina Y et al. Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution. Nat Genet. 2021.

• Mishina Y et al. Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate. Biomaterials. 2021.

• Moyer et al.Addressing the Impact of COVID-19 on the Residency Application Process Through a Virtual Subinternship. Otolaryngol Head Neck Surg. 2020

• Nor et al. Fabrication of Vascularized DPSC Constructs for Efficient Pulp Regeneration. J Dent Res. 2021.

• Nor et al. A Member-Centric Association. J Dent Res. 2021.

• Nör JE et al. mTOR Inhibition Ablates Cisplatin-Resistant Salivary Gland Cancer Stem Cells. J Dent Res. 2021.

• Nör JE et al. VEGFR1 primes a unique cohort of dental pulp stem cells for vasculogenic differentiation. Eur Cell Mater. 2021.

• Nör JE et al. Inverse and reciprocal regulation of p53/p21 and Bmi-1 modulates vasculogenic differentiation of dental pulp stem cells. Cell Death Dis. 2021.

• Parent et al.Seizure-Induced Neurogenesis: 1 Out of 3 Ain’t Bad. Epilepsy Curr. 2020

• Parent JM et al. Critical roles of ɑII spectrin in brain development and epileptic encephalopathy. J Clin Invest. 2018.

• Parent JM et al. Modeling genetic epilepsies in a dish. Dev Dyn. 2020.

• Parent JM et al. Altered synaptic drive onto birthdated dentate granule cells in experimental temporal lobe epilepsy. J Neurosci. 2019.

• Parent JM et al. Multimodal analysis of STRADA function in brain Development. Front Cell Neurosci. 2020.

• Parent JM et al. Variant-Specific Changes in Persistent or Resurgent Sodium Current in SCN8A-Related Epilepsy Patient-Derived Neurons. Brain. 2020.

• Parkos CA et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2021.

• Parkos CA et al. Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2. Mol Biol Cell. 2021.

• Parkos et al. Finding the sweet spot: glycosylation mediated regulation of intestinal inflammation. Mucosal Immunol. 2022.

• Parkos et al. SIRPα – CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen. PLoS One. 2022.

• Rao RC et al. Efficient serum-free derivation of oligodendrocyte precursors from neural stem cell-enriched cultures. Stem Cells. 2009.

• Rao RC et al. Dynamic patterns of histone lysine methylation in the developing retina. Invest Ophthalmol Vis Sci. 2010.

• Rao RC et al. Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1. Sci Rep. 2016.

• Rao RC et al. Stem Cells for Retinal Disease: A Perspective on the Promise and Perils. Am J Ophthalmol. 2017.

• Rao RC et al. p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells. Cell Rep. 2020.

• Rao RC et al. The endangered physician-scientist and COVID-19. Cell Rep Med. 2021.

• Ross et al. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem 2022.

• Scott et al. Iridium-Catalysed C−H Borylation of Heteroarenes: Balancing Steric and Electronic Regiocontrol. Angew Chem Int Ed Engl. 2021.

• Scott et al. On the consensus nomenclature rules for radiopharmaceutical chemistry – Reconsideration of radiochemical conversion. Nucl Med Biol. 2021.

• Scott et al. An updated synthesis of N1′-([11C]methyl)naltrindole for positron emission tomography imaging of the delta opioid receptor. J Labelled Comp Radiopharm. 2021.

• Scott et al. Radiofluorination of oxazole-carboxamides for preclinical PET neuroimaging of GSK-3. J Fluor Chem. 2021.

• Scott et al. A Comprehensive Assessment of 68Ga-PSMA-11 PET in Biochemically Recurrent Prostate Cancer: Results from a Prospective Multicenter Study on 2,005 Patients. J Nucl Med. 2022.

• Scott et al. Preclinical evaluation of (S)-[18F]GE387, a novel 18-kDa translocator protein (TSPO) PET radioligand with low binding sensitivity to human polymorphism rs6971. Eur J Nucl Med Mol Imaging. 2021.

• Scott et al. Potential Applications of Artificial Intelligence and Machine Learning in Radiochemistry and Radiochemical Engineering. PET Clin. 2021.

• Scott et al. Preliminary Evaluations of [11C]Verubulin: Implications for Microtubule Imaging With PET. Front Neurosci. 2021.

• Scott et al. Nuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development. J Nucl Med. 2022.

• Scott et al. Synthesis and Evaluation of a Fluorine-18 Radioligand for Imaging Huntingtin Aggregates by Positron Emission Tomographic Imaging. Front Neurosci. 2021.

• Scott et al. Synthesis of 68Ga-radiopharmaceuticals using both generator-derived and cyclotron-produced 68Ga as exemplified by [68Ga]Ga-PSMA-11 for prostate cancer PET imaging. Nat Protoc. 2022.

• Scott et al. No Dopamine Agonist Modulation of Brain [18F]FEOBV Binding in Parkinson’s Disease. Mol Pharm. 2022.

• Shea et al. Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering. Lancet Diabetes Endocrinol. 2021.

• Shea et al. Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis. Nat Commun. 2020.

• Shea et al. Tolerance induced by antigen-loaded plg nanoparticles affects the phenotype and trafficking of transgenic cd4+ and cd8+ t cells. Cells. 2021.

• Shea et al. Mechanistic contributions of Kupffer cells and liver sinusoidal endothelial cells in nanoparticle-induced antigen-specific immune tolerance. Biomaterials. 2022.

• Shea et al. Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss. Proc Natl Acad Sci U S A. 2022.

• Shea LD et al. Microporous scaffolds support assembly and differentiation of pancreatic progenitors into ß-cell clusters. Acta Biomater. 2019.

• Shea LD et al. Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. Proc Natl Acad Sci U S A. 2019.

• Shea LD et al. Metastatic Conditioning of Myeloid Cells at a Subcutaneous Synthetic Niche Reflects Disease Progression and Predicts Therapeutic Outcomes. Cancer Res. 2020.

• Shea LD et al. Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. Tissue Eng Part A. 2020.

• Shea LD et al. Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis. Nat Commun. 2020.

• Shea LD et al. An injectable PEG hydrogel controlling neurotrophin-3 release by affinity peptides. J Control Release. 2021.

• Shea LD et al. Disease-induced immunomodulation at biomaterial scaffolds detects early pancreatic cancer in a spontaneous model. Biomaterials. 2021.

• Shea LD et al. Cargo-free immunomodulatory nanoparticles combined with anti-PD-1 antibody for treating metastatic breast cancer. Biomaterials. 2021.

• Shea LD et al. IL-10 lentivirus-laden hydrogel tubes increase spinal progenitor survival and neuronal differentiation after spinal cord injury. Biotechnol Bioeng. 2021.

• Shtein et al. Kirigami-Based Compliant Mechanism for Multiaxis Optical Tracking and Energy-Harvesting Applications. Adv Eng Mat. 2021.

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