Musculoskeletal/Orthopedic
Musculoskeletal Disorders are injuries and disorders that affect the human body’s movement or musculoskeletal system, for example, the muscles, tendons, ligaments, nerves, discs, blood vessels, etc. Common disorders include Carpal Tunnel Syndrome, Tendonitis, and Muscle or Tendon strain.
Researchers
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Carlos AguilarEngineering -
Andrea AlfordMedicine -
Benjamin AllenMedicine -
Brendon BakerMedicine -
Marco BottinoDentistry -
Steven BuchmanMedicine -
Sriram ChandrasekaranMedicine -
Greg ClinesMedicine -
Mark CohenMedicine -
Rhima ColemanEngineering -
Catherine CollinsLSA -
Cheri DengEngineering
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Mario FabiilliMedicine -
Stephen FeinbergDentistry -
Renny FranceschiDentistry -
Kurt HankensonMedicine -
Nan HatchDentistry -
Darnell KaiglerDentistry
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Stephen KempMedicine
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Megan KillianMedicine -
David KohnDentistry -
Ken KozloffMedicine -
Lisa LarkinMedicine -
Liu LiuMedicine
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Brian LoveEngineering
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Laurie McCauleyDentistry -
Yuji MishinaDentistry -
Mary-Ann MycekEngineering
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Noriaki OnoDentistry -
Andy PutnamEngineering -
Brian RossMedicine
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Jan StegemannEngineering -
Megan WeivodaDentistry
Select Publications
Aguilar CA et al. Transcriptional and Chromatin Dynamics of Muscle Regeneration After Severe Trauma. Stem Cell Reports. 2016.
Aguilar CA et al. Multiscale analysis of a regenerative therapy for treatment of volumetric muscle loss injury. Cell Death Discov. 2018.
Aguilar CA et al. Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis. J Immunology. 2020.
Aguilar CA et al. Dissecting murine muscle stem cell aging through integrative genomic analysis. Cell Rep. 2020.
Aguilar CA et al. Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells. JCI Insight. 2020.
Aguilar CA et al. Engineered Tools to Study Intercellular Communication. Adv Sci (Weinh). 2021.
Aguilar CA et al. Metabolipidomic profiling reveals an age-related deficiency of skeletal muscle pro-resolving mediators that contributes to maladaptive tissue remodeling. Aging Cell. 2021.
Aguilar et al. Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss. Commun Biol. 2020.
Alford AI et al. Two molecular weight species of thrombospondin-2 are present in bone and differentially modulated in fractured and nonfractured tibiae in a murine model of bone healing. Calcif Tissue Int. 2012.
Alford AI et al. Thrombospondin-2 facilitates assembly of a type-I collagen rich matrix in marrow stromal cells undergoing osteoblastic differentiation. Connect Tissue Res. 2013.
Alford AI et al. Thrombospondin-2 deficiency in growing mice alters bone collagen ultrastructure and leads to a brittle bone phenotype. J Appl Physiol. 1985.
Alford AI et al. TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro. Connect Tissue Res. 2019.
Alford AI et al. Evaluation of global gene expression in regenerate tissues during Masquelet treatment. J Orthop Res. 2020.
Alford AI et al. Intersite reliability of vertebral bone marrow lipidomics-derived lipid composition among children with varying degrees of bone fragility undergoing routine orthopedic surgery. Bone. 2021.
Alford AI et al. Pattern of bone marrow lipid composition measures along the vertebral column: A descriptive study of adolescents with idiopathic scoliosis. Bone. 2021.
Alford AI et al. Masquelet’s induced membrane technique: Review of current concepts and future directions. J Orthop Res. 2021.
Allen BL et al. Dosage-dependent regulation of pancreatic cancer growth and angiogenesis by hedgehog signaling. Cell Rep. 2014.
Allen BL et al. Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function. J Biol Chem. 2015.
Allen BL et al. Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif. J Biol Chem. 2017.
Allen BL et al. Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib. Proc Natl Acad Sci U S A. 2017.
Allen BL et al. The Hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development. Development. 2020.
Allen BL et al. Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer. Clin Cancer Res. 2021.
Baker BM et al. Matrix degradability controls multicellularity of 3D cell migration. Nat Commun. 2017.
Baker BM et al. Cell force-mediated matrix reorganization underlies multicellular network assembly. Sci Rep. 2019.
Baker BM et al. Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration. Nat Commun. 2019.
Baker BM et al. Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation. Lab Chip. 2020.
Baker BM et al. Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in idiopathic pulmonary fibrosis. Sci Adv. 2020.
Baker BM et al. Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices. Biomater Sci. 2021.
Baker BM et al. Stable and transient bubble formation in acoustically-responsive scaffolds by acoustic droplet vaporization: theory and application in sequential release. Ultrason Sonochem. 2021.
Baker BM et al. Stromal cell identity modulates vascular morphogenesis in a microvasculature-on-a-chip platform. Lab Chip. 2021.
Baker BM et al. New directions and dimensions for bioengineered models of fibrosis. Nat Review Mater. 2021.
Bottino MC et al. A novel patient-specific three-dimensional drug delivery construct for regenerative endodontics. J Biomed Mater Res B Appl Biomater. 2019.
Bottino MC et al. Injectable MMP-Responsive Nanotube-Modified Gelatin Hydrogel for Dental Infection Ablation. ACS Appl Mater Interfaces. 2020.
Bottino MC et al. Extracellular Matrix/Amorphous Magnesium Phosphate Bioink for 3D Bioprinting of Craniomaxillofacial Bone Tissue. ACS Appl Mater Interfaces. 2020.
Bottino MC et al. Highly tunable bioactive fiber-reinforced hydrogel for guided bone regeneration. Acta Biomater. 2020.
Bottino MC et al. Hybrid Antimicrobial Hydrogel as Injectable Therapeutics for Oral Infection Ablation. Biomacromolecules. 2020.
Bottino MC et al. The role of nanohydroxyapatite on the morphological, physical, and biological properties of chitosan nanofibers. Clin Oral Investig. 2021.
Bottino MC et al. Development and properties of endodontic resin sealers with natural oils. J Dent. 2021.
Bottino MC et al. Metformin-loaded nanospheres-laden photocrosslinkable gelatin hydrogel for bone tissue engineering. J Mech Behav Biomed Mater. 2021.
Buchman SR et al. Radioprotection With Amifostine Enhances Bone Strength and Regeneration and Bony Union in a Rat Model of Mandibular Distraction Osteogenesis. Ann Plast Surg. 2018.
Buchman SR et al. Topical Deferoxamine Alleviates Skin Injury and Normalizes Atomic Force Microscopy Patterns Following Radiation in a Murine Breast Reconstruction Model. Ann Plast Surg. 2018.
Buchman SR et al. Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment. J Craniofac Surg. 2019.
Buchman SR et al. The Role of Deferoxamine in Irradiated Breast Reconstruction: A Study of Oncologic Safety. Plast Reconstr Sur. 2019.
Buchman SR et al. Implantable hyaluronic acid-deferoxamine conjugate prevents nonunions through stimulation of neovascularization. NPJ Regen Med. 2019.
Buchman SR et al. A Simplified Approach to Myelomeningocele Defect Repair. Ann Plast Surg. 2021.
Buchman SR et al. Achieving the Optimal Aesthetic Benefit While Correcting Midface Deficiency: Utilizing A High Winged Le Fort I in Cleft and Craniofacial Patients. J Craniofac Surg. 2021.
Cederna et al. Aesthetic Surgery in Plastic Surgery Academia. Aesthet Surg J. 2021.
Cederna PS et al. Reinventing Extremity Amputation in the Era of Functional Limb Restoration. Ann Surg. 2021.
Cederna PS et al. Developing Strategies for Targeted Improvement of Perioperative Education for Postbariatric Surgery Body-Contouring Patients. Ann Plast Surg. 2021.
Cederna PS et al. Regenerative peripheral nerve interface free muscle graft mass and function. Muscle Nerve. 2021.
Chandrasekaran et al. Purine metabolism regulates DNA repair and therapy resistance in glioblastoma. Nat Commun. 2020.
Chandrasekaran et al. The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. J Clin Invest. 2021.
Chandrasekaran S et al. LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. Cell Stem Cell. 2016.
Chandrasekaran S et al. Comprehensive mapping of pluripotent stem cell metabolism using dynamic genome-scale network modeling. Cell Rep. 2017.
Chandrasekaran S et al. Genome-scale network model of metabolism and histone acetylation reveals metabolic dependencies of histone deacetylase inhibitors. Genome Biol. 2019.
Chandrasekaran S et al. Dynamic Network Modeling of Stem Cell Metabolism, Methods in Molecular Biology: Computational Stem Cell Biology. Methods Mol Biol. 2019.
Chandrasekaran S et al. Nutrient Sensing by Histone Marks: Reading the Metabolic Histone Code Using Tracing, Omics, and Modeling. Bioessays. 2020.
Clines GA et al. Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor. J Bone Miner Res. 2011.
Clines GA et al. Dural Cells Release Factors Which Promote Cancer Cell Malignancy and Induce Immunosuppressive Markers in Bone Marrow Myeloid Cells. Neurosurgery. 2018.
Clines GA et al. DKK1 and Kremen Expression Predicts the Osteoblastic Response to Bone Metastasis. Transl Oncol. 2018.
Clines GA et al. The challenges of diagnosing osteoporosis and the limitations of currently available tools. Clin Diabetes Endocrinol. 2018.
Clines GA et al. Castration Determines the Efficacy of ETAR Blockade in a Mouse Model of Prostate Cancer Bone Metastasis. Endocrinology. 2019.
Cohen et al. A novel heat shock protein inhibitor KU757 with efficacy in lenvatinib-resistant follicular thyroid cancer cells overcomes up-regulated glycolysis in drug-resistant cells in vitro. Surgery. 2021.
Cohen et al. Early biochemical response to parathyroidectomy for primary hyperparathyroidism and its predictive value for recurrent hypercalcemia and recurrent primary hyperparathyroidism. Surgery. 2021.
Cohen et al. Practical Guidance for Early Identification of Barriers in Surgical Telehealth Clinics. Ann Surg. 2021.
Cohen et al. LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy. Nat Cell Biol. 2021.
Collins CA et al. Mitochondrial fission, integrity and clearance require separable functions of Vps13D in Drosophila neurons. bioRxiv. 2020.
Collins CA et al. Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol. 2010.
Collins CA et al. The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol. 2012.
Collins CA et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. eLife. 2016.
Collins CA et al. Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. Elife. 2017.
Deng CX et al. Injectable pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivo. Sci Rep. 2020.
Deng CX et al. Microscale Characterization of the Viscoelastic Properties of Hydrogel Biomaterials using Ultrasound Technique. Biomaterials. 2016.
Deng CX et al. Acoustic tweezing cytometry enhances osteogenesis of human mesenchymal stem cells through cytoskeletal contractility and YAP activation. Biomaterials. 2017.
Deng CX et al. Multimode Ultrasound Viscoelastography for Three-Dimensional Interrogation of Microscale Mechanical Properties in Heterogeneous Biomaterials. Biomaterials. 2018.
Deng CX et al. Acoustic actuation of integrin-bound microbubbles for mechanical phenotyping during differentiation and morphogenesis of human embryonic stem cells. Small. 2018.
Deng CX et al. Integrin-targeted Cyclic Forces Accelerate Neural Tube-like Rosette Formation from Human Embryonic Stem Cells. Adv Biosyst. 2019.
Deng CX et al. Visualization and quantification of dynamic intercellular coupling in human embryonic stem cells using single cell sonoporation. Sci Rep. 2020.
Deng CX et al. Resonant acoustic rheometry for non-contact characterization of viscoelastic biomaterials. Biomaterials. 2021.
Deng CX et al. High Frequency Spectral Ultrasound Imaging Detects Early Heterotopic Ossification in Rodents. Stem Cells Dev. 2021.
Dressler et al. Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021.
Duncan RK et al. Matrigel is required for efficient differentiation of isolated, stem cell-derived otic vesicles into inner ear organoids. Stem Cell Res. 2021.
Edwards et al. Dental students’ OMFS-related experiences and interest in OMFS careers: An exploration. J Dent Educ. 2021.
Edwards et al. Squamous Cell Carcinoma of the Tongue in Young Patients: A Case Series and Literature Review. J Oral Maxillofac Surg. 2021.
Fabiilli et al. Spatially-directed angiogenesis using ultrasound-controlled release of basic fibroblast growth factor from acoustically-responsive scaffolds. Acta Biomater. 2021.
Fabiilli ML et al. Spatiotemporally-controlled transgene expression in hydroxyapatite-fibrin composite scaffolds using high intensity focused ultrasound. Biomaterials. 2019.
Fabiilli ML et al. Controlled delivery of basic fibroblast growth factor (bFGF) using acoustic droplet vaporization stimulates endothelial network formation. Acta Biomater. 2019.
Fabiilli ML et al. Standing wave-assisted acoustic droplet vaporization for single and dual payload release in acoustically-responsive scaffolds. Ultrason Sonochem. 2020.
Fabiilli ML et al. Spatially-directed cell migration in acoustically-responsive scaffolds via the controlled delivery of basic fibroblast growth factor. Acta Biomater. 2020.
Fabiilli ML et al. Spatiotemporal control of micromechanics and microstructure in acoustically-responsive scaffolds using acoustic droplet vaporization. Soft Matter. 2020.
Fabiilli ML et al. Stable and transient bubble formation in acoustically-responsive scaffolds by acoustic droplet vaporization: theory and application in sequential release. Ultrason Sonochem. 2021.
Feinberg SE et al. Tissue engineering of lips and muco-cutaneous junctions: in vitro development of tissue engineered constructs of oral mucosa and skin for lip reconstruction. Tissue Eng Part C Methods. 2012.
Feinberg SE et al. Intraoral grafting of tissue-engineered human oral mucosa. Int J Oral Maxillofac Implants. 2013.
Feinberg SE et al. Fabrication of Large Size Ex Vivo-Produced Oral Mucosal Equivalents for Clinical Application. Tissue Eng Part C Methods. 2015.
Feinberg SE et al. In Vitro Development of a Mucocutaneous Junction for Lip Reconstruction. J Oral Maxillofac Surg. 2016.
Feinberg SE et al. Soft Tissue Engineering. Oral Maxillofac Surg Clin North Am. 2017.
Feldman EL et al. Amyotrophic Lateral Sclerosis Survival Associates With Neutrophils in a Sex-specific Manner. Neurol Neuroimmunol Neuroinflamm. 2021.
Franceschi RT et al. Advanced BMP gene therapies for temporal and spatial control of bone regeneration. J Dent Res. 2013.
Franceschi RT et al. Discoidin Domain Receptor 2 Controls Bone Formation and Marrow Adipogenesis. J Bone Miner Res. 2016.
Franceschi RT et al. Control of the osteoblast lineage by mitogen-activated protein kinase signaling. Curr Mol Biol Rep. 2017.
Franceschi RT et al. Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. J Dent Res. 2018.
Franceschi RT et al. Genetic inhibition of PPAR-gamma S112 phosphorylation reduces bone formation and stimulates marrow adipogenesis. Bone. 2018.
Franceschi RT et al. Patient perceptions of SARS-CoV-2 exposure risk and association with continuity of ophthalmic care. JAMA Opthalmol. 2021.
Franceschi RT et al. Spatially-directed angiogenesis using ultrasound-controlled release of basic fibroblast growth factor from acoustically-responsive scaffolds. Acta Biomater. 2021.
Fu J et al. Stem-cell-based embryo models for fundamental research and translation. Nat Mater. 2021.
Green GE et al. Modified Minerva Cervical Thoracic Orthosis for Postoperative Management of Cricotracheal Resection. Ear Nose Throat J. 2021.
Green GE et al. Competency-Based Assessment Tool for Pediatric Esophagoscopy: International Modified Delphi Consensus. Laryngoscope. 2021.
Hammer GD et al. What Did We Learn from the Molecular Biology of Adrenal Cortical Neoplasia? From Histopathology to Translational Genomics. Endocr Pathol. 2021.
Hankenson KD et al. Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects. NPJ Regen Med. 2017.
Hankenson KD et al. R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass. Bone Res. 2018.
Hankenson KD et al. Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density. Nat Commun. 2019.
Hankenson KD et al. CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing. J Orthop Res. 2020.
Hankenson KD et al. Thrombospondin-2 spatiotemporal expression in skeletal fractures. J Orthop Res. 2021.
Hankenson KD et al. Canonical Notch signaling is required for bone morphogenetic protein-mediated human osteoblast differentiation. Stem Cells. 2020.
Hankenson KD et al. Biological constraints on gwas snps at suggestive significance thresholds reveal additional bmi loci. Elife. 2021.
Hankenson KD et al. Silver-doped bioactive glass particles for in vivo bone tissue regeneration and enhanced methicillin-resistant Staphylococcus aureus (MRSA) inhibition. Mater Sci Eng C Mater Biol Appl. 2021.
Hatch NE et al. Tissue-nonspecific Alkaline Phosphatase Deficiency Causes Abnormal Craniofacial Bone Development in the Alpl-/- Mouse Model of Infantile Hypophosphatasia. Bone. 2014.
Hatch NE et al. Microsphere controlled drug delivery for local control of tooth movement. Eur J Orthod. 2019.
Hatch NE et al. Tissue nonspecific alkaline phosphatase promotes calvarial progenitor cell cycle progression and cytokinesis via Erk1,2. Bone. 2019.
Hatch NE et al. Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2C342Y/+ mouse models of Crouzon syndrome. PLoS One. 2020.
Hatch NE et al. Genetic background dependent modifiers of craniosynostosis severity. J Struct Biol. 2020.
Kemp et al. Regenerative peripheral nerve interface free muscle graft mass and function. Muscle Nerve. 2021.
Kemp SWP et al.The clinical significance of a swollen neuroma: A meaningful distinction or an incidental finding? Ann Palliat Med. 2020
Killian ML et al. Effects of imbalanced muscle loading on hip joint development and maturation. J Orthop Res. 2017.
Killian ML et al. Partial-width injuries of the rat rotator cuff heal with fibrosis. Connect Tissue Res. 2018.
Killian ML et al. Novel model for the induction of postnatal murine hip deformity. J Orthop Res. 2019.
Killian ML et al. Photobiomodulation does not influence maturation and mildly improves functional healing of mouse achilles tendons. J Orthop Res. 2020.
Killian ML et al. Optogenetic activation of muscle contraction in vivo. Connect Tissue Res. 2020.
Killian ML et al. Optogenetic activation of muscle contraction in vivo. Connect Tissue Res. 2021.
Kohn DH et al. Connexin 43 as a signaling platform for increasing the volume and spatial distribution of regenerated tissue. Proc Natl Acad Sci U S A. 2009.
Kohn DH et al. Gene delivery via DNA incorporation within a biomimetic apatite coating. Biomaterials. 2009.
Kohn DH et al. PTH signaling mediates perilacunar remodeling during exercise. Matrix Biol. 2016.
Kohn DH et al. Dual-functioning peptides discovered by phage display increase the magnitude and specificity of BMSC attachment to mineralized biomaterials. Biomaterials. 2017.
Kohn DH et al. Cell and material-specific phage display peptides increase iPS-MSC mediated bone and vasculature formation in vivo. Adv Healthc Mater. 2019.
Kozloff et al.Bone chemical composition assessment with multi-wavelength photoacoustic analysis. Front Physics. 2020
Kozloff KM et al. Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo. J Bone Miner Res. 2010.
Kozloff KM et al. Osteoblast response to ovariectomy is enhanced in intrinsically high aerobic capacity rats. Calcif Tissue Int. 2011.
Kozloff KM et al. Adult Brtl/+ mouse model of osteogenesis imperfecta demonstrates anabolic response to sclerostin antibody treatment with increased bone mass and strength. Osteoporos Int. 2014.
Kozloff KM et al. Rapidly growing Brtl/+ mouse model of osteogenesis imperfecta improves bone mass and strength with sclerostin antibody treatment. Bone. 2015.
Kozloff KM et al. Low dose of bisphosphonate enhances sclerostin antibody-induced trabecular bone mass gains in Brtl/+ osteogenesis imperfecta mouse model. J Bone Miner Res. 2018.
Kozloff, KM et al. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020.
Liu AP et al. Human induced pluripotent stem cell-derived lung organoids in an ex vivo model of the congenital diaphragmatic hernia fetal lung. Stem Cells Transl Med. 2021.
Liu L et al. MicroRNA-181a regulates local immune balance by inhibiting proliferation and immunosuppressive properties of mesenchymal stem cells. Stem Cells. 2012.
Liu L et al. Mesenchymal stem cells ameliorate Th1-induced pre-eclampsia-like symptoms in mice via the suppression of TNF-α expression. PLoS One. 2014.
Liu L et al. Improving cardiac reprogramming for heart regeneration. Curr Opin Organ Transplant. 2016.
Liu L et al. Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts. Cell Discov. 2016.
Liu L et al. Chemical suppression of specific C-C chemokine signaling pathways enhances cardiac reprogramming. J Biol Chem. 2019.
Love et al. A meta-analysis of bone cement mediated antibiotic release: Overkill, but a viable approach to eradicate osteomyelitis and other infections tied to open procedures. Mater Sci Eng C Mater Biol Appl. 2021.
Love et al. Swellable catheters based on a dynamic expanding inner diameter. J Mater Sci Mater Med. 2021.
McCauley LK et al. Local pulsatile PTH delivery regenerates bone defects via enhanced bone remodeling in a cell-free scaffold. Biomaterials. 2017.
McCauley LK et al. Macrophages and skeletal health. Pharmacol Ther. 2017.
McCauley LK et al. Apoptosis-induced CXCL5 accelerates inflammation and growth of prostate tumor metastases in bone. J Clin Invest. 2018.
McCauley LK et al. Inflammatory bone loss associated with MFG-E8 deficiency is rescued by teriparatide. FASEB J. 2018.
McCauley LK et al. Clodronate-loaded liposome treatment has site-specific skeletal effects. J Dent Res. 2019.
McCauley LK et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020.
McCauley LK et al. Impact of COVID-19 on Life Experiences of Essential Workers Attending a Dental Testing Facility. JDR Clin Trans Res. 2021.
Mehta et al. The MEK1/2 pathway as a therapeutic target in high-grade serous ovarian carcinoma. Cancers (Basel). 2021.
Mehta G et al. Design and applications of surfaces that control the accretion of matter. Sci. 2021.
Mishina Y et al. Quantification of three-dimensional morphology of craniofacial mineralized tissue defects in Tgfbr2/Osx-Cre mice. Oral Sci Int. 2021.
Mishina Y et al. Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation. Sci Signal. 2021.
Mishina Y et al. BMP type I receptor inhibition prevents ectopic ossification in a mouse model of fibrodysplasia ossificans progressiva. Nat Med. 2008.
Mishina Y et al. Augmented BMP signaling in neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis. Development. 2015.
Mishina Y et al. Coordinating Tissue Regeneration Through Transforming Growth Factor-β Activated Kinase 1 Inactivation and Reactivation. Stem Cells. 2019.
Mishina Y et al. Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway. J Biol Chem. 2019.
Mishina Y et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020.
Mishina Y et al. Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes depending on anatomical positions of the bones in mice. Bone. 2020.
Mycek et al. Noninvasive Optical Assessment of Implanted Tissue-Engineered Construct Success in Situ. Tissue Eng Part C Methods. 2021.
Mycek et al.Needle-compatible miniaturized optoelectronic sensor for pancreatic cancer detection. Sci Adv. 2020
Ono N et al. Diverse contribution of Col2a1-expressing cells to the craniofacial skeletal cell lineages. Orthod Craniofac Res. 2017.
Ono N et al. Msx2 Marks Spatially Restricted Populations of Mesenchymal Precursors. J Dent Res. 2018.
Ono N et al. Resting zone of the growth plate houses a unique class of skeletal stem cells. Nature. 2018.
Ono N et al. Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells. J Bone Miner Res. 2019.
Ono N et al. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020.
Ono N et al. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020.
Putnam AJ et al. Stromal Cell Identity Influences the In Vivo Functionality of Engineered Capillary Networks Formed by Co-Delivery of Endothelial Cells and Stromal Cells. Tissue Eng Part A. 2013.
Putnam AJ et al. Protease-Sensitive PEG Hydrogels Regulate Vascularization In Vitro and In Vivo. Macromol Biosci. 2014.
Putnam AJ et al. Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D cultures. Sci Rep. 2018.
Putnam AJ et al. A Systems Mechanobiology Model to Predict Cardiac Reprogramming Outcomes on Different Biomaterials. Biomaterials. 2018.
Putnam AJ et al. Cell-mediated matrix stiffening accompanies capillary morphogenesis in ultrasoft amorphous hydrogels. Biomaterials. 2020.
Putnam AJ et al. Injectable pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivo. Sci Rep. 2020.
Ross et al. Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution. Nat Commun. 2020.
Shikanov A et al. Swellable catheters based on a dynamic expanding inner diameter. J Mater Sci Mater Med. 2021.
Si et al. Unicuspid Aortic Valve Repair Using Geometric Ring Annuloplasty. Ann Thorac Surg. 2021.
Si et al. Berlin Heart EXCOR and ACTION post-approval surveillance study report. J Heart Lung Transplant 2021.
Si et al. Right heart failure considerations in pediatric ventricular assist devices. Pediatr Transplant. 2021.
Soleimanpour SA et al. Cell Cycle Regulation of the Pdx1 Transcription Factor in Developing Pancreas and Insulin-Producing β-Cells. Diabetes. 2021.
Spence et al. Mapping Development of the Human Intestinal Niche at Single-Cell Resolution. Cell Stem Cell. 2021.
Spence et al. Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk. Cell Stem Cell. 2021.
Spence et al. SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol. 2021.
Spence et al. NH2-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. Am J Physiol Gastrointest Liver Physiol. 2021.
Spence et al. Charting human development using a multi-endodermal organ atlas and organoid models. Cell. 2021.
Stegemann JP et al. Injectable pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivo. Sci Rep. 2020.
Wang CW Is periodontal phenotypic conversion therapy beneficial for patients receiving orthodontic treatment? An American Academy of Periodontology Best Evidence Review. J Periodontol. 2020.
Wang H-L et al. Creating a virtual patient for completely edentulous computer-aided implant surgery: A dental technique. J Prosthet Dent. 2021.
Wang H-L et al. Influence of bone density, drill diameter, drilling speed, and irrigation on temperature changes during implant osteotomies: an in vitro study. Clin Oral Investig. 2021.
Wang H-L et al. Suppuration as diagnostic criterium of peri-implantitis. J Periodontol. 2021.
Wang H-L et al. Acellular dermal matrix for root coverage procedures: 9-year assessment of treated isolated gingival recessions and their adjacent untreated sites. J Periodontol. 2021.
Wang H-L et al. Laser-assisted regenerative surgical therapy for peri-implantitis: A randomized controlled clinical trial. J Periodontol. 2021.
Wang H-L et al. Indirect Digital Workflow for Virtual Cross-Mounting of Fixed Implant-Supported Prostheses to Create a 3D Virtual Patient. J Prosthodont. 2021.
Wang H-L et al. Influence of restorative design on the progression of peri-implant bone loss: A retrospective study. J Periodontol. 2021.
Wang H-L et al. The influence of the interaction between staging, grading and extent on tooth loss due to periodontitis. J Clin Periodontol. 2021.
Wang H-L et al. Intra-osseous heat generation during implant bed preparation with static navigation: Multi-factor in vitro study. Clin Oral Implants Res. 2021.
Wang HL et al. Efficacy of platelet-rich fibrin on socket healing after mandibular third molar extractions. J Oral and Maxillofac Surg. 2021.
Weivoda et al. Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020.
Weivoda MM et al. Osteoclast TGF-ß receptor signaling induces Wnt1 secretion and couples bone resorption to bone formation. J Bone Miner Res. 2016.
Weivoda MM et al. Targeting senescent cells enhances adipogenesis and metabolic function in old age. Elife. 2015.
Weivoda MM et al. Targeting cellular senescence prevents age-related bone loss in mice. Nat Med. 2017.
Weivoda MM et al. Senolytics improve physical function and increase lifespan in old age. Nat Med. 2018.
Weivoda MM et al. Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020.