Dental/Oral/Craniofacial

Reconstruction of dental, oral, and craniofacial tissues through tissue engineering and/or regenerative medicine is a major goal in dentistry. Research in this area includes the study of craniofacial/skeletal biology and disease including cancer and guided regenerative interventions for tissues lost due to disease or trauma.

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Allen BL et al. Dosage-dependent regulation of pancreatic cancer growth and angiogenesis by hedgehog signaling. Cell Rep. 2014.
Allen BL et al. Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function. J Biol Chem. 2015.
Allen BL et al. Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif. J Biol Chem. 2017.
Allen BL et al. Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib. Proc Natl Acad Sci U S A. 2017.
Allen BL et al. The Hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development. Development. 2020.
Arruda et al. Investigation of Fiber-Driven Mechanical Behavior of Human and Porcine Bladder Tissue Tested Under Identical Conditions. J Biomech Eng. 2021.
Arruda et al. The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review. J Biomech Eng. 2022.
Arruda et al. Ogden material calibration via magnetic resonance cartography, parameter sensitivity and variational system identification. Philos Trans A Math Phys Eng Sci. 2022.
Arruda et al. Topological transformability and reprogrammability of multistable mechanical metamaterials. Proc Natl Acad Sci U S A. 2022.
Arruda et al. Constitutive modeling of the anterior cruciate ligament bundles and patellar tendon with full-field methods. J Mech Phys Solids. 2021.
Arruda et al. Inference of deformation mechanisms and constitutive response of soft material surrogates of biological tissue by full-field characterization and data-driven variational system identification. J Mech A Solid 2021.
Baker BM et al. Matrix degradability controls multicellularity of 3D cell migration. Nat Commun. 2017.
Baker BM et al. Cell force-mediated matrix reorganization underlies multicellular network assembly. Sci Rep. 2019.
Baker BM et al. Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration. Nat Commun. 2019.
Baker BM et al. Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation. Lab Chip. 2020.
Baker BM et al. Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in idiopathic pulmonary fibrosis. Sci Adv. 2020.
Baker BM et al. Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices. Biomater Sci. 2021.
Baker BM et al. Stable and transient bubble formation in acoustically-responsive scaffolds by acoustic droplet vaporization: theory and application in sequential release. Ultrason Sonochem. 2021.
Baker BM et al. Stromal cell identity modulates vascular morphogenesis in a microvasculature-on-a-chip platform. Lab Chip. 2021.
Baker BM et al. New directions and dimensions for bioengineered models of fibrosis. Nat Review Mater. 2021.
Baker BM et al. Quantification and immunoprofiling of bladder cancer cell-derived extracellular vesicles with microfluidic chemiluminescent ELISA. Biosens Bioelectron: X. 2021.
Baker et al. Physical and Soluble Cues Enhance Tendon Progenitor Cell Invasion into Injectable Synthetic Hydrogels. Adv Funct Mater. 2022.
Baker et al. Sequestered cell-secreted extracellular matrix proteins improve murine folliculogenesis and oocyte maturation for fertility preservation. Acta Biomater. 2021.
Baker et al. Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology. Adv Mater. 2021.
Baker et al. Spatiotemporal control of myofibroblast activation in acoustically-responsive scaffolds via ultrasound-induced matrix stiffening. Acta Biomater. 2022.
Baker et al. Micropatterning of acoustic droplet vaporization in acoustically-responsive scaffolds using extrusion-based bioprinting. Bioprinting. 2022.
Baker et al. Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D. Adv Sci (weinh). 2022.
Baker et al. The living interface between synthetic biology and biomaterial design. Nat Mater. 2022.
Baker et al. Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization. Sci Adv. 2022.
Bottino et al. Three-dimensional printing of clinical scale and personalized calcium phosphate scaffolds for alveolar bone reconstruction. Dent Mater. 2022.
Bottino et al. Platform technologies for regenerative endodontics from multifunctional biomaterials to tooth-on-a-chip strategies. Clin Oral Investig. 2021.
Bottino et al. A Highly Ordered, Nanostructured Fluorinated CaP-Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration. Adv Healthc Mater. 2021.
Bottino et al. Dental education 2026: A scenario exploration. J Dent Educ. 2022.
Bottino et al. Scenario IV: Under-resourced but resilient and transformative. J Dent Educ. 2022.
Bottino et al. Do resin cement viscosity and ceramic surface etching influence the fatigue performance of bonded lithium disilicate glass-ceramic crowns?. Dent Mater. 2022.
Bottino et al. Novel cinnamon-laden nanofibers as a potential antifungal coating for poly(methyl methacrylate) denture base materials. Clin Oral Investig. 2022.
Bottino et al. Engineering of Injectable Antibiotic-Laden Fibrous Microparticles Gelatin Methacryloyl Hydrogel for Endodontic Infection Ablation. Int J Mol Sci. 2022.
Bottino et al. Influence of ethylenediaminetetraacetic acid on regenerative endodontics: A systematic review. Int Endod J. 2022.
Bottino et al. Photocrosslinkable methacrylated gelatin hydrogel as a cell-friendly injectable delivery system for chlorhexidine in regenerative endodontics. Dent Mater. 2022.
Bottino et al. Thickness and internal adjustment of monolithic resin composite milled crowns: Effect on the load-bearing capacity under fatigue. J Mech Behav Biomed Mater. 2022.
Bottino et al. Advanced biomaterials for periodontal tissue regeneration. Genesis. 2022.
Bottino et al. Self-assembling peptide-laden electrospun scaffolds for guided mineralized tissue regeneration. Dent Mater. 2022.
Bottino et al. Development of functional fillers as a self-healing system for dental resin composite. J Dent. 2022.
Bottino et al. Adhesion to a new CAD/CAM resin composite: Effects of the machining roughness simulation, surface treatments, and long-term aging. Int J Adhes Adhes. 2022.
Bottino MC et al. A novel patient-specific three-dimensional drug delivery construct for regenerative endodontics. J Biomed Mater Res B Appl Biomater. 2019.
Bottino MC et al. Injectable MMP-Responsive Nanotube-Modified Gelatin Hydrogel for Dental Infection Ablation. ACS Appl Mater Interfaces. 2020.
Bottino MC et al. Extracellular Matrix/Amorphous Magnesium Phosphate Bioink for 3D Bioprinting of Craniomaxillofacial Bone Tissue. ACS Appl Mater Interfaces. 2020.
Bottino MC et al. Highly tunable bioactive fiber-reinforced hydrogel for guided bone regeneration. Acta Biomater. 2020.
Bottino MC et al. Hybrid Antimicrobial Hydrogel as Injectable Therapeutics for Oral Infection Ablation. Biomacromolecules. 2020.
Bottino MC et al. The role of nanohydroxyapatite on the morphological, physical, and biological properties of chitosan nanofibers. Clin Oral Investig. 2021.
Bottino MC et al. Development and properties of endodontic resin sealers with natural oils. J Dent. 2021.
Bottino MC et al. Metformin-loaded nanospheres-laden photocrosslinkable gelatin hydrogel for bone tissue engineering. J Mech Behav Biomed Mater. 2021.
Bottino MC et al. Alumina particle air-abrasion and aging effects: Fatigue behavior of CAD/CAM resin composite crowns and flexural strength evaluations. J Mech Behav Biomed Mater. 2021.
Buchman et al. Association between habitual snoring, middle ear disease, and speech problems in young children with non-syndromic cleft palate anomalies. Int J Oral Maxillofac Surg. 2022.
Buchman et al. Impact of sleep-disordered breathing on behavior and quality of life in children aged 2 to 7 years with non-syndromic cleft lip and/or palate. Pediatr Pulmonol. 2021.
Buchman et al. Institutional trends in opioid prescribing and utilization after primary cleft lip and palate repair. Plast Reconstr Surg. 2022.
Buchman et al. Reply: Management of Calcified Cephalohematoma of Infancy: The University of Michigan 25-Year Experience. Plast Reconstr Surg. 2022.
Buchman SR et al. Radioprotection With Amifostine Enhances Bone Strength and Regeneration and Bony Union in a Rat Model of Mandibular Distraction Osteogenesis. Ann Plast Surg. 2018.
Buchman SR et al. Topical Deferoxamine Alleviates Skin Injury and Normalizes Atomic Force Microscopy Patterns Following Radiation in a Murine Breast Reconstruction Model. Ann Plast Surg. 2018.
Buchman SR et al. Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment. J Craniofac Surg. 2019.
Buchman SR et al. The Role of Deferoxamine in Irradiated Breast Reconstruction: A Study of Oncologic Safety. Plast Reconstr Sur. 2019.
Buchman SR et al. Implantable hyaluronic acid-deferoxamine conjugate prevents nonunions through stimulation of neovascularization. NPJ Regen Med. 2019.
Buchman SR et al. A Simplified Approach to Myelomeningocele Defect Repair. Ann Plast Surg. 2021.
Buchman SR et al. Achieving the Optimal Aesthetic Benefit While Correcting Midface Deficiency: Utilizing A High Winged Le Fort I in Cleft and Craniofacial Patients. J Craniofac Surg. 2021.
Buchman SR et al. Sleep-related movement disorders and growing pains: differences in daytime and bedtime behavior in 2–6 year old children with cleft palate. Sleep Med. 2021.
Camper et al. Comprehensive Identification of Pathogenic Gene Variants in Patients With Neuroendocrine Disorders. J Clin Endocrinol Metab. 2021.
Camper et al. The phenotypic spectrum associated with OTX2 mutations in humans. Eur J Endocrinol. 2021.
Camper et al. Novel mechanism of pituitary hormone deficiency: genetic variants shift splicing to produce a dominant negative transcription factor isoform. Eur J Endocrinol. 2021.
Camper et al. Novel genes and variants associated with congenital pituitary hormone deficiency in the era of next-generation sequencing. Front Endocrinol (Lausanne). 2022.
Camper SA et al. Genetics of Combined Pituitary Hormone Deficiency: Roadmap into the Genome Era. Endocr Rev. 2016.
Camper SA et al. Next generation sequencing panel based on single molecule molecular inversion probes for detecting genetic variants in children with hypopituitarism. Mol Genet Genomic Med. 2018.
Camper SA et al. PROP1-Dependent Retinoic Acid Signaling Regulates Developmental Pituitary Morphogenesis and Hormone Expression. Endocrinology. 2020.
Camper SA et al. Otx2b mutant zebrafish have pituitary, eye and mandible defects that model mammalian disease. Hum Mol Genet. 2020.
Camper SA et al. Rathke’s cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020.
Camper SA et al. High-throughput splicing assays identify missense and silent splice-disruptive POU1F1 variants underlying pituitary hormone deficiency. Am J Hum Genet. 2021.
Cederna PS et al. Impact of Human Epidermal Growth Factor on Tissue-Engineered Skeletal Muscle Structure and Function. Tissue Eng Part A. 2021.
Chandrasekaran et al. The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. J Clin Invest. 2021.
Cohen et al. A novel heat shock protein inhibitor KU757 with efficacy in lenvatinib-resistant follicular thyroid cancer cells overcomes up-regulated glycolysis in drug-resistant cells in vitro. Surgery. 2021.
Cohen et al. Early biochemical response to parathyroidectomy for primary hyperparathyroidism and its predictive value for recurrent hypercalcemia and recurrent primary hyperparathyroidism. Surgery. 2021.
Cohen et al. Practical Guidance for Early Identification of Barriers in Surgical Telehealth Clinics. Ann Surg. 2021.
Cohen et al. LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy. Nat Cell Biol. 2021.
Cohen et al. Identification of novel lipid metabolic biomarkers associated with poor adrenocortical carcinoma prognosis using integrated bioinformatics. Surgery. 2022.
Cohen et al. Re-evaluation of combinational efficacy and synergy of the italian protocol in vitro: Are we truly optimizing benefit or permitting unwanted toxicity?. Biomedicines. 2021.
Collins CA et al. Mitochondrial fission, integrity and clearance require separable functions of Vps13D in Drosophila neurons. bioRxiv. 2020.
Collins CA et al. Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol. 2010.
Collins CA et al. The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol. 2012.
Collins CA et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. eLife. 2016.
Collins CA et al. Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. Elife. 2017.
Deng CX et al. Resonant acoustic rheometry for non-contact characterization of viscoelastic biomaterials. Biomaterials. 2021.
Deng CX et al. High Frequency Spectral Ultrasound Imaging Detects Early Heterotopic Ossification in Rodents. Stem Cells Dev. 2021.
Dressler et al. Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021.
Dressler et al. Identification of Pax protein inhibitors that suppress target gene expression and cancer cell proliferation. Cell Chem Biol. 2022.
Duan C et al. Hypoxia converts the myogenic action of insulin-like growth factors into mitogenic action by differentially regulating multiple signaling pathways. Proc Natl Acad Sci U S A. 2010.
Duan C et al. Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Cell Rep. 2014.
Duan C et al. Ca2+ concentration-dependent premature death of igfbp5a mutant zebrafish reveals a critical role of IGF signaling in adaptive epithelial growth. Sci Signal. 2018.
Duan C et al. Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6. Elife. 2019.
Duan C et al. The metalloproteinase Papp-aa controls epithelial cell quiescence to proliferation transition. Elife. 2020.
Duan et al. Calcium State-Dependent Regulation of Epithelial Cell Quiescence by Stanniocalcin 1a. Front Cell Dev Biol. 2021.
Duan et al. IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish. Gen Comp Endocrinol. 2021.
Duncan et al. The nematode C. elegans senses airborne sound. Neuron. 2021.
Duncan et al. Measurements From Ears With Endolymphatic Hydrops and 2-Hydroxypropyl-Beta-Cyclodextrin Provide Evidence That Loudness Recruitment Can Have a Cochlear Origin. Front Surg. 2021.
Duncan RK et al. Matrigel is required for efficient differentiation of isolated, stem cell-derived otic vesicles into inner ear organoids. Stem Cell Res. 2021.
Fabiilli ML et al. Spatiotemporally-controlled transgene expression in hydroxyapatite-fibrin composite scaffolds using high intensity focused ultrasound. Biomaterials. 2019.
Fabiilli ML et al. Controlled delivery of basic fibroblast growth factor (bFGF) using acoustic droplet vaporization stimulates endothelial network formation. Acta Biomater. 2019.
Fabiilli ML et al. Standing wave-assisted acoustic droplet vaporization for single and dual payload release in acoustically-responsive scaffolds. Ultrason Sonochem. 2020.
Fabiilli ML et al. Spatially-directed cell migration in acoustically-responsive scaffolds via the controlled delivery of basic fibroblast growth factor. Acta Biomater. 2020.
Fabiilli ML et al. Spatiotemporal control of micromechanics and microstructure in acoustically-responsive scaffolds using acoustic droplet vaporization. Soft Matter. 2020.
Feinberg SE et al. Tissue engineering of lips and muco-cutaneous junctions: in vitro development of tissue engineered constructs of oral mucosa and skin for lip reconstruction. Tissue Eng Part C Methods. 2012.
Feinberg SE et al. Intraoral grafting of tissue-engineered human oral mucosa. Int J Oral Maxillofac Implants. 2013.
Feinberg SE et al. Fabrication of Large Size Ex Vivo-Produced Oral Mucosal Equivalents for Clinical Application. Tissue Eng Part C Methods. 2015.
Feinberg SE et al. In Vitro Development of a Mucocutaneous Junction for Lip Reconstruction. J Oral Maxillofac Surg. 2016.
Feinberg SE et al. Soft Tissue Engineering. Oral Maxillofac Surg Clin North Am. 2017.
Feldman EL et al. Amyotrophic Lateral Sclerosis Survival Associates With Neutrophils in a Sex-specific Manner. Neurol Neuroimmunol Neuroinflamm. 2021.
Franceschi et al. Release of basic fibroblast growth factor from acoustically-responsive scaffolds promotes therapeutic angiogenesis in the hind limb ischemia model. J Control Release. 2021.
Franceschi et al. Role of Discoidin Domain Receptor 2 in Craniofacial Bone Regeneration. J Dent Res. 2021.
Franceschi et al. Spatiotemporal control of myofibroblast activation in acoustically-responsive scaffolds via ultrasound-induced matrix stiffening. Acta Biomater. 2022.
Franceschi et al. Expression of Beta-Catenin, Cadherins and P-Runx2 in Fibro-Osseous Lesions of the Jaw: Tissue Microarray Study. Biomolecules. 2022.
Franceschi et al. Cranial Base Synchondrosis: Chondrocytes at the Hub. Int J Mol Sci. 2022.
Franceschi et al. Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization. Sci Adv. 2022.
Franceschi RT et al. Advanced BMP gene therapies for temporal and spatial control of bone regeneration. J Dent Res. 2013.
Franceschi RT et al. Discoidin Domain Receptor 2 Controls Bone Formation and Marrow Adipogenesis. J Bone Miner Res. 2016.
Franceschi RT et al. Control of the osteoblast lineage by mitogen-activated protein kinase signaling. Curr Mol Biol Rep. 2017.
Franceschi RT et al. Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. J Dent Res. 2018.
Franceschi RT et al. Genetic inhibition of PPAR-gamma S112 phosphorylation reduces bone formation and stimulates marrow adipogenesis. Bone. 2018.
Franceschi RT et al. Patient perceptions of SARS-CoV-2 exposure risk and association with continuity of ophthalmic care. JAMA Opthalmol. 2021.
Goldman et al. Notch signaling via Hey1 and Id2b regulates Müller glia’s regenerative response to retinal injury. Glia. 2021.
Goldman et al. Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration. Proc Natl Acad Sci U S A. 2022.
Green et al. Tracheal agenesis: Esophageal airway support with a 3-dimensional–printed bioresorbable splint. JTCVS Tech. 2021.
Green et al. Addressing the Pandemic Training Deficiency: Filling the Void with Simulation in Facial Reconstruction. Laryngoscope. 2021.
Green et al. A national pediatric otolaryngology fellowship virtual dissection course using 3D printed simulators. Int J Pediatr Otorhinolaryngol. 2022.
Green GE et al. Bioresorbable Airway Splint Created with a Three-Dimensional Printer. N Engl J Med. 2013.
Green GE et al. Mitigation of tracheobronchomalacia with 3D-printed personalized medical devices in pediatric patients. Sci Transl Med. 2015.
Green GE et al. Regulatory Considerations in the Design and Manufacturing of Implantable 3D-Printed Medical Devices. Clin Transl Sci. 2015.
Green GE et al. Co-culture of adipose-derived stem cells and chondrocytes on three-dimensionally printed bioscaffolds for craniofacial cartilage engineering. Laryngoscope. 2018.
Green GE et al. Modified Minerva Cervical Thoracic Orthosis for Postoperative Management of Cricotracheal Resection. Ear Nose Throat J. 2021.
Green GE et al. Competency-Based Assessment Tool for Pediatric Esophagoscopy: International Modified Delphi Consensus. Laryngoscope. 2021.
Green GE et al. Evaluating Directional Dependency of Selective Laser Sintered Patient Specific Biodegradable Devices to Improve Predictive Modeling and Design Verification. Ann Biomed Eng. 2021.
Green GE et al. Characterization of noise exposure in places of worship. Appl Acoust. 2021.
Hammer et al. American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary. JAMA Surg. 2022.
Hammer GD et al. What Did We Learn from the Molecular Biology of Adrenal Cortical Neoplasia? From Histopathology to Translational Genomics. Endocr Pathol. 2021.
Hankenson et al. Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone. 2021.
Hankenson et al. Constitutive bone marrow adipocytes suppress local bone formation. JCI Insight. 2022.
Hankenson KD et al. Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects. NPJ Regen Med. 2017.
Hankenson KD et al. R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass. Bone Res. 2018.
Hankenson KD et al. Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density. Nat Commun. 2019.
Hankenson KD et al. CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing. J Orthop Res. 2020.
Hankenson KD et al. Thrombospondin-2 spatiotemporal expression in skeletal fractures. J Orthop Res. 2021.
Hankenson KD et al. Canonical Notch signaling is required for bone morphogenetic protein-mediated human osteoblast differentiation. Stem Cells. 2020.
Hankenson KD et al. Biological constraints on gwas snps at suggestive significance thresholds reveal additional bmi loci. Elife. 2021.
Hankenson KD et al. Silver-doped bioactive glass particles for in vivo bone tissue regeneration and enhanced methicillin-resistant Staphylococcus aureus (MRSA) inhibition. Mater Sci Eng C Mater Biol Appl. 2021.
Hankenson KD et al. CRISPR-Cas9–Mediated Genome Editing Confirms EPDR1 as an Effector Gene at the BMD GWAS-Implicated ‘STARD3NL’ Locus. JBMR Plus. 2021.
Harder et al. Molecular programs associated with glomerular hyperfiltration in early diabetic kidney disease. Kidney Int. 2022.
Hatch NE et al. Tissue-nonspecific Alkaline Phosphatase Deficiency Causes Abnormal Craniofacial Bone Development in the Alpl-/- Mouse Model of Infantile Hypophosphatasia. Bone. 2014.
Hatch NE et al. Microsphere controlled drug delivery for local control of tooth movement. Eur J Orthod. 2019.
Hatch NE et al. Tissue nonspecific alkaline phosphatase promotes calvarial progenitor cell cycle progression and cytokinesis via Erk1,2. Bone. 2019.
Hatch NE et al. Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2C342Y/+ mouse models of Crouzon syndrome. PLoS One. 2020.
Hatch NE et al. Genetic background dependent modifiers of craniosynostosis severity. J Struct Biol. 2020.
Hatch NE et al. Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate. Biomaterials. 2021.
Kaigler et al. Three-dimensional printing of clinical scale and personalized calcium phosphate scaffolds for alveolar bone reconstruction. Dent Mater. 2022.
Kaigler et al. Dual Digitally Guided Crown Lengthening in Esthetic Area Compromised by Disharmonic Implant Crown. Clin Adv Periodontics. 2022.
Kaigler et al. Phenotypic, trophic, and regenerative properties of mesenchymal stem cells from different osseous tissues. Cell Tissue Res. 2022.
Kemp et al. Comparison of Outcomes of Spinal Accessory to Suprascapular Nerve Transfer Versus Nerve Grafting for Neonatal Brachial Plexus Injury. Orthopedics. 2022.
Kemp et al. The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals. J Vis Exp. 2022.
Kemp et al. Regenerative peripheral nerve interface free muscle graft mass and function. Muscle Nerve. 2021.
Kemp et al. “Decreasing Postamputation Pain with the Regenerative Peripheral Nerve Interface (RPNI)”. Ann Vasc Surg. 2022.
Kemp et al. Ultraflexible and Stretchable Intrafascicular Peripheral Nerve Recording Device with Axon-Dimension, Cuff-Less Microneedle Electrode Array. Small. 2022.
Kemp et al. Pathophysiological and Neuroplastic Changes in Postamputation and Neuropathic Pain: Review of the Literature. Plast Reconstr Surg Glob Open. 2022.
Kohn DH et al. Connexin 43 as a signaling platform for increasing the volume and spatial distribution of regenerated tissue. Proc Natl Acad Sci U S A. 2009.
Kohn DH et al. Gene delivery via DNA incorporation within a biomimetic apatite coating. Biomaterials. 2009.
Kohn DH et al. PTH signaling mediates perilacunar remodeling during exercise. Matrix Biol. 2016.
Kohn DH et al. Dual-functioning peptides discovered by phage display increase the magnitude and specificity of BMSC attachment to mineralized biomaterials. Biomaterials. 2017.
Kohn DH et al. Cell and material-specific phage display peptides increase iPS-MSC mediated bone and vasculature formation in vivo. Adv Healthc Mater. 2019.
Kozloff et al. Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone. 2021.
Kozloff et al. Systemic administration of recombinant irisin accelerates fracture healing in mice. Int J Mol Sci. 2021.
Kozloff et al. Position-Specific Physical Workload Intensities in American Collegiate Football Training. J Strength Cond Res. 2022.
Kozloff et al. Tibial nerve stimulation increases vaginal blood perfusion and bone mineral density and yield load in ovariectomized rat menopause model. Int Urogynecol J. 2022.
Kozloff et al. Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study. J Struct Biol. 2022.
Kozloff KM et al. In vivo quantitative imaging biomarkers of bone quality and mineral density using multi-band-SWIFT magnetic resonance imaging. Bone. 2021.
Kozloff KM et al. Altered collagen chemical compositional structure in osteopenic women with past fractures: A case-control Raman spectroscopic study. Bone. 2021.
Kozloff KM et al. The feasibility study of the transmission mode photoacoustic measurement of human calcaneus bone in vivo. Photoacoustics. 2021.
Lahann et al. Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy. Nat Commun. 2020.
Lahann J et al. Cooperative Switching in Large‐Area Assemblies of Magnetic Janus Particles. Adv Funct Mater. 2020.
Lahann J et al. 3D Jet Writing: Functional Microtissues Based on Tessellated Scaffold Architectures. Adv Mater. 2018.
Lahann J et al. Templated nanofiber synthesis via chemical vapor polymerization into liquid crystalline films. Science. 2018.
Lahann J et al. Engineered Fibrillar Fibronectin Networks as Three Dimensional Tissue Scaffolds. Adv Mater. 2019.
Lahann J et al. Multifunctional Synthetic Protein Nanoparticles via Reactive Electrojetting. Macromol Rapid Commun. 2020.
Lahann J et al. Stepwise cell seeding on tessellated scaffolds to study sprouting blood vessels. J Vis Exp. 2021.
Lahann J et al. Targeting gliomas with STAT3-silencing nanoparticles. Mol Cell Onc. 2021.
Larkin et al. Impact of Human Epidermal Growth Factor on Tissue-Engineered Skeletal Muscle Structure and Function. Tissue Eng Part A. 2021.
Larkin et al. Impact of Cell Seeding Density and Cell Confluence on Human Tissue Engineered Skeletal Muscle. Tissue Eng Part A. 2022.
Larkin et al. Repairing Volumetric Muscle Loss in the Ovine Peroneus Tertius Following a 6-Month Recovery. Tissue Eng Part A. 2022.
Larkin et al. Morphologic and histologic characterization of sheep and porcine TMJ as large animal models for tissue engineering applications. Clin Oral Investig. 2022.
Liu et al. Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells. J Biol Chem. 2022.
Lombard DB et al. The deacylase SIRT5 supports melanoma viability by regulating chromatin dynamics. bioRxiv. 2020.
Lombard DB et al. SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013.
Lombard DB et al. Canagliflozin extends lifespan in genetically heterogeneous male but not female mice. JCI Insight. 2020.
Lombard DB et al. Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology. Crit Rev Biochem Mol Biol. 2018.
Lombard DB et al. High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv. 2020.
Lombard DB et al. Melanoma models for the next generation of therapies. Cancer Cell. 2021.
Lombard DB et al. The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. J Clin Invest. 2021.
Lombard et al. High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions. Commun Biol. 2020.
Lombard et al. An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells. Sci Rep. 2020.
Lombard et al. ER stress protein PERK promotes inappropriate innate immune responses and pathogenesis during RSV infection. J Leukoc Biol. 2022.
Lombard et al. SIRT5’s GOT1 up on PDAC. Gastroenterology. 2021.
Lombard et al. Canagliflozin Increases Intestinal Adenoma Burden in Female ApcMin/+ Mice. J Gerontol A Biol Sci Med Sci. 2022.
Lombard et al. Metabolic Requirement for GOT2 in Pancreatic Cancer Depends on Environmental Context. Elife. 2022.
Lombard et al. Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors. Eur J Med Chem. 2022.
Lombard et al.Canagliflozin extends life span in genetically heterogeneous male but not female mice. JCI Insight. 2020
McCauley LK et al. Local pulsatile PTH delivery regenerates bone defects via enhanced bone remodeling in a cell-free scaffold. Biomaterials. 2017.
McCauley LK et al. Macrophages and skeletal health. Pharmacol Ther. 2017.
McCauley LK et al. Apoptosis-induced CXCL5 accelerates inflammation and growth of prostate tumor metastases in bone. J Clin Invest. 2018.
McCauley LK et al. Inflammatory bone loss associated with MFG-E8 deficiency is rescued by teriparatide. FASEB J. 2018.
McCauley LK et al. Clodronate-loaded liposome treatment has site-specific skeletal effects. J Dent Res. 2019.
McCauley LK et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020.
McCauley LK et al. Impact of COVID-19 on Life Experiences of Essential Workers Attending a Dental Testing Facility. JDR Clin Trans Res. 2021.
Mehta et al. Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers. Cancers (Basel). 2022.
Mehta et al. The MEK1/2 pathway as a therapeutic target in high-grade serous ovarian carcinoma. Cancers (Basel). 2021.
Mehta et al. Injectable three-dimensional tumor microenvironments to study mechanobiology in ovarian cancer. Acta Biomater. 2022.
Mehta G et al. Personalized models of heterogeneous 3D epithelial tumor microenvironments: Ovarian cancer as a model. Acta Biomater. 2021.
Mehta G et al. Design and applications of surfaces that control the accretion of matter. Sci. 2021.
Mishina Y et al. Quantification of three-dimensional morphology of craniofacial mineralized tissue defects in Tgfbr2/Osx-Cre mice. Oral Sci Int. 2021.
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